Bone hemostasis
Encyclopedia
Bone hemostasis is the process of controlling the bleeding from bone
Bone
Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support, and protect the various organs of the body, produce red and white blood cells and store minerals. Bone tissue is a type of dense connective tissue...

.

Bone is a living vascular organ
Organ (anatomy)
In biology, an organ is a collection of tissues joined in structural unit to serve a common function. Usually there is a main tissue and sporadic tissues . The main tissue is the one that is unique for the specific organ. For example, main tissue in the heart is the myocardium, while sporadic are...

 containing channels for blood
Blood
Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....

 and bone marrow
Bone marrow
Bone marrow is the flexible tissue found in the interior of bones. In humans, bone marrow in large bones produces new blood cells. On average, bone marrow constitutes 4% of the total body mass of humans; in adults weighing 65 kg , bone marrow accounts for approximately 2.6 kg...

. When a bone is cut during surgery bleeding can be a difficult problem to control, especially in the highly vascular bones of the spine
Vertebral column
In human anatomy, the vertebral column is a column usually consisting of 24 articulating vertebrae, and 9 fused vertebrae in the sacrum and the coccyx. It is situated in the dorsal aspect of the torso, separated by intervertebral discs...

 and sternum. Bleeding from soft tissue is normally stopped using a cautery that creates heat, causing blood vessels to collapse and become sealed. Since the blood in living bone flows through channels in the bone that do not collapse, a cautery is not effective in preventing bone bleeding. Blocking the holes in the bone typically stops bone bleeding. This can be done by mechanically blocking the holes (tamponade effect), or by inducing a blood clot to form.

In the past the easiest and most common way to stop bone bleeding was to apply bone wax
Bone wax
Bone wax is used to help mechanically control bleeding from bone surfaces during surgical procedures.It is made of beeswax with a softening agent such as paraffin or vasoline and is smeared across the bleeding edge of the bone, blocking the holes and causing immediate bone hemostasis through a...

, which is made from beeswax
Beeswax
Beeswax is a natural wax produced in the bee hive of honey bees of the genus Apis. It is mainly esters of fatty acids and various long chain alcohols...

. The bone wax is smeared across the bleeding edge of the bone, blocking the holes and causing immediate hemostasis. Because of the complications associated with the use of bone wax, newer water soluble hemostatic agents, such as those made from alkylene oxide copolymers have been developed.
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