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Bismuth subsalicylate

 

 
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Bismuth subsalicylate
 
 
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Bismuth subsalicylate, with a chemical formula C7H5BiO4, is a drug used to treat nausea
Nausea

Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
, heartburn
Heartburn

Heartburn or pyrosis is a painful and burning sensation in the esophagus, just below the Sternum usually associated with regurgitation of gastric acid....
, indigestion, diarrhea
Diarrhea

In medicine, diarrhea, also spelled diarrhoea , is characterized by frequent loose or liquid bowel movements. The spelling of "diarrhea" is an appropriation of the Greek "diarrhoia" meaning "a flowing through." ....
, and other temporary discomforts of the stomach
Stomach

In most mammals, the stomach is a hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication....
 and gastrointestinal tract
Gastrointestinal tract

The digestive tract is the system of Organ s within multicellular animals that takes in food, digestion it to extract energy and nutrients, and expels the remaining waste....
. Commonly known as pink bismuth, it is the active ingredient in popular medications such as Pepto-Bismol
Pepto-Bismol

Pepto-Bismol is an over-the-counter drug produced by the Procter and Gamble company in the United States of America and in Canada to treat minor digestive system upset....
 and (modern) Kaopectate.

derivative of salicylic acid
Salicylic acid

Salicylic acid is a beta hydroxy acid with the chemical formula C6H4COOH, where the OH group is adjacent to the carboxylic acid....
, bismuth
Bismuth

Bismuth is a chemical element that has the symbol Bi and atomic number 83. This heavy, brittle, white crystalline trivalent poor metal has a pink tinge and chemically resembles arsenic and antimony....
 salicylate displays anti-inflammatory
Anti-inflammatory

Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids which affect the brain....
 action and also acts as an antacid
Antacid

An antacid is any substance, generally a Base or basic salt, which counteracts gastric acid. In other words, antacids are stomach acid neutralization ....
.

e are some adverse effects
Adverse effect (medicine)

In medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as chemotherapy or surgery....
.






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Bismuth subsalicylate, with a chemical formula C7H5BiO4, is a drug used to treat nausea
Nausea

Nausea is the sensation of unease and discomfort in the stomach with an urge to vomit....
, heartburn
Heartburn

Heartburn or pyrosis is a painful and burning sensation in the esophagus, just below the Sternum usually associated with regurgitation of gastric acid....
, indigestion, diarrhea
Diarrhea

In medicine, diarrhea, also spelled diarrhoea , is characterized by frequent loose or liquid bowel movements. The spelling of "diarrhea" is an appropriation of the Greek "diarrhoia" meaning "a flowing through." ....
, and other temporary discomforts of the stomach
Stomach

In most mammals, the stomach is a hollow muscular organ of the gastrointestinal tract involved in the second phase of digestion, following mastication....
 and gastrointestinal tract
Gastrointestinal tract

The digestive tract is the system of Organ s within multicellular animals that takes in food, digestion it to extract energy and nutrients, and expels the remaining waste....
. Commonly known as pink bismuth, it is the active ingredient in popular medications such as Pepto-Bismol
Pepto-Bismol

Pepto-Bismol is an over-the-counter drug produced by the Procter and Gamble company in the United States of America and in Canada to treat minor digestive system upset....
 and (modern) Kaopectate.

Pharmacology

As a derivative of salicylic acid
Salicylic acid

Salicylic acid is a beta hydroxy acid with the chemical formula C6H4COOH, where the OH group is adjacent to the carboxylic acid....
, bismuth
Bismuth

Bismuth is a chemical element that has the symbol Bi and atomic number 83. This heavy, brittle, white crystalline trivalent poor metal has a pink tinge and chemically resembles arsenic and antimony....
 salicylate displays anti-inflammatory
Anti-inflammatory

Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids which affect the brain....
 action and also acts as an antacid
Antacid

An antacid is any substance, generally a Base or basic salt, which counteracts gastric acid. In other words, antacids are stomach acid neutralization ....
.

Adverse effects and contraindications

There are some adverse effects
Adverse effect (medicine)

In medicine, an adverse effect is a harmful and undesired effect resulting from a medication or other intervention such as chemotherapy or surgery....
. It can also cause a black tongue and black stools
Feces

Feces, faeces, or f?ces is a waste product from an animal's gastrointestinal tract expelled through the anus during defecation....
 in some users of the drug, when it combines with trace amounts of sulfur
Sulfur

Sulfur or sulphur is the chemical element that has the atomic number 16. It is denoted with the symbol S. It is an abundant Valence non-metal....
 in their saliva and gastrointestinal tract. This discoloration is temporary and harmless.

Some of the risks of salicylism can apply to the use of bismuth subsalicylate.

Children should not take medication with bismuth subsalicylate while recovering from influenza
Influenza

Influenza, commonly known as the flu, is an infectious disease that affects birds and mammals caused by RNA viruses of the biological family Orthomyxoviridae ....
 or chicken pox, as epidemiologic evidence points to an association between the use of salicylate-containing medications during certain viral infections and the onset of Reye's syndrome
Reye's syndrome

Reye's syndrome is a potentially fatal disease that causes numerous detrimental effects to many organs, especially the brain and liver. It is associated with aspirin consumption by children with viral diseases such as chickenpox....
. For the same reason, it is typically recommended that nursing mothers not use medication containing bismuth subsalicylate (such as Pepto-Bismol) because small amounts of the medication are excreted in breast milk and pose a theoretical risk of Reye's syndrome to nursing children.

Radioactivity

While bismuth
Bismuth

Bismuth is a chemical element that has the symbol Bi and atomic number 83. This heavy, brittle, white crystalline trivalent poor metal has a pink tinge and chemically resembles arsenic and antimony....
 is technically radioactive
Radioactive decay

Radioactive decay is the process in which an unstable atomic nucleus loses energy by emitting ionizing particles and radiation. This decay, or loss of energy, results in an atom of one type, called the parent nuclide transforming to an atom of a different type, called the daughter nuclide....
, its half life is so long, on the order of hundreds of billions of years
1 E19 s and more

To help compare orders of magnitude of different times, this page lists times longer than 1019 seconds . See also Heat death of the universe....
, that it is safe for all medical and other ordinary purposes.