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Gastrointestinal tract

The gastrointestinal tract or digestive tract, also referred to as the GI tract or the alimentary canal, or the gut, is the system of organs within multicellular animals which takes in food Food

Food is any substance, usually comprised primarily of carbohydrate [i]s, fat [i]s, vitamins, water and/o ... 

, digests it to extract energy and nutrient Nutrient

A nutrient is any element or compound necessary for or contributing to an organism's metabolism [i], gro ... 

s, and expels the remaining waste. This process is called digestion Digestion

For the industrial process see anaerobic digestion [i] ... 

. The GI tract differs substantially from animal to animal. For instance, some animals have multi-chambered stomachs. Reference:

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The gastrointestinal tract or digestive tract, also referred to as the GI tract or the alimentary canal, or the gut, is the system of organs within multicellular animals which takes in food Food

Food is any substance, usually comprised primarily of carbohydrate [i]s, fat [i]s, vitamins, water and/o ... 

, digests it to extract energy and nutrient Nutrient

A nutrient is any element or compound necessary for or contributing to an organism's metabolism [i], gro ... 

s, and expels the remaining waste. This process is called digestion Digestion

For the industrial process see anaerobic digestion [i]
... 

.

The GI tract differs substantially from animal to animal. For instance, some animals have multi-chambered stomachs.
Reference:


Basic anatomy


The gut


In a normal human Human

Humans, or human beings, are biped [i]al primate [i]s belonging to the mammal [i]ian species ... 

 adult male, the GI tract is approximately 7.5 meters long and consists of the following components:
Upper gastrointestinal tract
  • Mouth Mouth

    The mouth, also known as the buccal cavity or the oral cavity, is the opening through which ... 

  • Pharynx
  • Oesophagus Esophagus

    The esophagus, or gullet is the muscular tube in vertebrate [i]s through which ingested food passe ... 

     or Esophagus Esophagus

    The esophagus, or gullet is the muscular tube in vertebrate [i]s through which ingested food passe ... 

      and cardia Cardia

    The cardia is the anatomical [i] term for the junction orifice of the stomach [i] and the esophagus [i] ... 

  • Stomach Stomach

    In anatomy [i], the stomach is an organ [i] in the gastrointestinal tract [i] used to digest [i] ... 

    , which includes the antrum and pylorus and pyloric sphincter.

Lower gastrointestinal tract
  • Bowel or intestine Intestine

    In anatomy [i], the intestine is the portion of the alimentary canal [i] extendin ... 

    :
    • small intestine Small intestine

      In biology [i] the small intestine [i] is the part of the gastrointestinal tract [i] between the stomach [i] ... 

      , which has three parts:
      • duodenum
      • jejunum Jejunum

        In anatomy [i] of the digestive system [i], the jejunum is the central of the three divisions of the small intestine [i] ... 

      • ileum Ileum

        In anatomy [i] of the digestive system [i], the ileum is the final section of the small intestine [i]. ... 

    • large intestine, which has three parts:
      • caecum .
      • colon
      • rectum
  • anus Anus

    In anatomy [i], the anus is the external opening of the rectum [i]. ... 



Related organs

The liver Liver

The liver is an organ [i] in vertebrate [i]s, including human [i]s. ... 

 secretes bile into the small intestine via the biliary system, employing the gallbladder Gallbladder

The gallbladder is a pear-shaped organ [i] that stores about 50 mL of bile [i] until the body need ... 

 as a reservoir. The pancreas Pancreas

The pancreas is an organ in the digestive system that serves two major functions:
... 

 secretes an isosmotic fluid containing bicarbonate and several enzymes, including trypsin, chymotrypsin Chymotrypsin

Chymotrypsin is a digestive enzyme that can perform proteolysis [i]. ... 

, lipase Lipase

A lipase is is a water-soluble [i] enzyme [i] that catalyze [i]s the hydrolysis [i] of ester [i] bonds [i] ... 

, and pancreatic amylase Amylase

Amylase is the name given to enzymes [i] that break down starch [i]. ... 

, as well as nucleolytic enzymes , into the small intestine. Both these secretory organs aid in digestion Digestion

For the industrial process see anaerobic digestion [i]
... 

.

Physiology


Specialization of organs

Four organs are subject to specialization in the kingdom Animalia Animal

Animals are a major group of organism [i]s, classified as the kingdom [i] Animalia or ... 

.

  • The first organ is the tongue Tongue

    The tongue is the large bundle of skeletal muscle [i]s on the floor of the mouth [i] that manipulates fo ... 

    which is only present in the phylum Chordata Chordate

    Chordates are a group of animal [i]s that includes the vertebrate [i]s, together with several closely ... 

    .
  • The second organ is the esophagus Esophagus

    The esophagus, or gullet is the muscular tube in vertebrate [i]s through which ingested food passe ... 

    . The crop is an enlargement of the esophagus in birds, insects and other invertebrates that is used to store food temporarily.
  • The third organ is the stomach Stomach

    In anatomy [i], the stomach is an organ [i] in the gastrointestinal tract [i] used to digest [i] ... 

    . In addition to a glandular stomach , birds have a muscular "stomach" called the ventriculus or "gizzard." The gizzard is used to mechanically grind up food.
  • The fourth organ is the large intestine. An outpouching of the large intestine called the cecum is present in non-ruminant herbivores such as rabbits. It aids in digestion of plant material such as cellulose Cellulose

    Cellulose

n
is a long-chain polymer [i]ic polysaccharide [i] carbohydrate [i], of beta-glucose [i] ... 

.

Immune function

The gastrointestinal tract is also a prominent part of the immune system Immune system

The immune system is composed of a complex constellation of cells, organs and tissues, arranged in an el... 

 . The low pH PH

pH is a measure of the acidity [i] of a solution [i], in terms of activity [i] of hydrogen [i] ... 

  of the stomach is fatal Death

Death is the full cessation of vital functions [i] in the biological life [i]. ... 

 for many microorganisms Microorganism

A microorganism or microbe is an organism [i] that is microscopic [i] . ... 

 that enter it. Similarly, mucus  neutralizes many of these microorganisms. Other factors in the GI tract help with immune function as well, including enzyme Enzyme

Enzymes are protein [i]s that accelerate, or catalyze [i], chemical reaction [i]s. ... 

s in the saliva and bile. Health enhancing intestinal bacteria serve to prevent the overgrowth of potentially harmful bacteria Bacteria

Bacteria are a major group of living organism [i]s. ... 

 in the gut.

Histology

The GI tract has a uniform general histology with some differences which reflect the specialization in functional anatomy. The GI tract can be divided into 4 concentric layers:
  • mucosa
  • submucosa Submucosa

    In the gastrointestinal tract.... 

  • muscularis externa
  • adventitia or serosa Serous membrane

    In anatomy [i], a serous membrane or serosa is a smooth membrane [i] consisting of a t ... 



Mucosa

The mucosa is the innermost layer of the GI tract, surrounding the lumen, or space within the tube. This layer comes in direct contact with the food , and is responsible for absorption and secretion, important processes in digestion.

The mucosa can be divided into:
  • epithelium
  • lamina propria
  • muscularis mucosae Muscularis mucosae

    The thin layer of smooth muscle [i] found in most parts of the gastrointestinal tract [i] located outside the ... 




The mucosa are highly specialized in each organ of the GI tract, facing a low pH in the stomach, absorbing a multitude of different substances in the small intestine, and also absorbing specific quantities of water in the large intestine. Reflecting the varying needs of these organs, the structure of the mucosa can consist of invaginations of secretory glands , or it can be folded in order to increase surface area .

Submucosa

The submucosa consists of a dense irregular layer of connective tissue with large blood vessels, lymphatics and nerves branching into the mucosa and muscularis. It contains Meissner's plexus, an enteric nervous plexa, situated on the inner surface of the muscularis externa.

Muscularis externa

The muscularis externa consists of a circular inner muscular layer and a longitudinal outer muscular layer. The circular muscle layer prevents the food from going backwards and the longitudinal layer shortens the tract. The coordinated contractions of these layers is called peristalsis Peristalsis

In the digestive tract, the muscularis externa propels the material along the alimentary canal.... 

 and propels the bolus, or balled-up food, through the GI tract.
Between the two muscle layers are the myenteric or Auerbach's plexa.

Adventitia/Serosa

The adventitia consists of several layers of connective tissue.
When the adventitia is facing the mesentery or peritoneal fold, the adventitia is covered by a mesothelium supported by a thin connective tissue layer, together forming a serosa, or serous membrane.

Uses of gut

  • The use of animal gut strings by musicians can be traced back to the third dynasty of Egypt. In the recent past, strings were made out of lamb Domestic sheep

    The domestic sheep , the most common species of the sheep genus , is a woolly ruminant [i] quadruped [i]... 

     gut. With the advent of the modern era, musicians have tended to use synthetic strings made of nylon, silk or steel. Some instrumentalists, however, still use gut strings in order to evoke the older tone quality. Although such strings were commonly referred to as "catgut" strings, cats were never used as a source for gut strings.
  • Sheep gut was the original source for natural gut string used in racquet Racquet

    A racquet is a sports implement consisting of a handled frame with an open hoop across which a network ... 

    s, such as for tennis Tennis

    Tennis is a game played between either two players or two teams of two players .... 

    . Today, synthetic strings are much more common, but the best strings are now made out of cow Cattle

    Cattle are domesticated [i] ungulate [i]s, a member of the subfamily [i] Bovinae [i] of t ... 

     gut.
  • Gut cord has also been used to produce strings for the snares which provide the snare drum Snare drum

    The snare drum or side drum is a tubular drum [i] made of wood [i] or metal [i] with skins, or head [i] ... 

    's characteristic buzzing timbre. While the snare drum currently almost always uses metal wire rather than gut cord, the North Africa North Africa

    North Africa or Northern Africa is the northernmost [i] region [i] of the Africa [i]n continent [i] ... 

    n bendir Bendir

    The bendir is a frame drum used as a traditional instrument throughout North Africa [i], more specifical... 

     frame drum still uses gut for this purpose.
  • "Natural" sausage hulls are made of animal gut, especially hog, beef, and lamb.
  • Animal gut was used to make the cord lines in longcase clock Longcase clock

    A longcase clock, also tall-case clock, grandfather clock or floor clock, is a freesta... 

    s, but may be replaced by wire.

References

  • National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health National Institutes of Health

    The National Institutes of Health is an agency of the United States Department of Health and Human Services [i] ... 

    .
  • Coico, R., Sunshine, G., and Benjamini, E. "Immunology: A short Course 5th ed." Pgs 11-12.
  • Kirszenbaum, A. Histology and Cell Biology, Mosby Inc. ISBN 0-323-01639-1 Pgs 401-402.

See also

  • Digestion Digestion

    For the industrial process see anaerobic digestion [i]

... 


  • Ingestion Eating

    In general terms, eating is the process of consuming something edible, i.e.... 

  • Excretion
  • Gastrointestinal hormone

External links