Benzilic acid
Encyclopedia
Benzilic acid is a white crystalline aromatic acid soluble in many primary alcohols. It can be prepared by heating mixture of benzil
, alcohol
and potassium hydroxide
. The other preparation way is through benzaldehyde
, which dimerizates to benzil
and it is further transformed by benzilic acid rearrangement
to benzilic acid. This reaction was also the first example of benzilic acid rearrangement
performed by Liebig in 1838.
Benzilic acid is used in organic synthesis, as a base point for preparation of glycollate pharmaceuticals and some hallucinogenic drugs.
Benzil
Benzil is the organic compound with the formula 2, generally abbreviated 2. This yellow solid is one of the most common diketones...
, alcohol
Alcohol
In chemistry, an alcohol is an organic compound in which the hydroxy functional group is bound to a carbon atom. In particular, this carbon center should be saturated, having single bonds to three other atoms....
and potassium hydroxide
Potassium hydroxide
Potassium hydroxide is an inorganic compound with the formula KOH, commonly called caustic potash.Along with sodium hydroxide , this colorless solid is a prototypical strong base. It has many industrial and niche applications. Most applications exploit its reactivity toward acids and its corrosive...
. The other preparation way is through benzaldehyde
Benzaldehyde
Benzaldehyde is an organic compound consisting of a benzene ring with a formyl substituent. It is the simplest aromatic aldehyde and one of the most industrially useful. This colorless liquid has a characteristic pleasant almond-like odor...
, which dimerizates to benzil
Benzil
Benzil is the organic compound with the formula 2, generally abbreviated 2. This yellow solid is one of the most common diketones...
and it is further transformed by benzilic acid rearrangement
Benzilic acid rearrangement
The benzilic acid rearrangement is the rearrangement reaction of benzil with potassium hydroxide to benzilic acid. First performed by Justus Liebig in 1838 this reaction type is displayed by 1,2-diketones in general...
to benzilic acid. This reaction was also the first example of benzilic acid rearrangement
Benzilic acid rearrangement
The benzilic acid rearrangement is the rearrangement reaction of benzil with potassium hydroxide to benzilic acid. First performed by Justus Liebig in 1838 this reaction type is displayed by 1,2-diketones in general...
performed by Liebig in 1838.
Benzilic acid is used in organic synthesis, as a base point for preparation of glycollate pharmaceuticals and some hallucinogenic drugs.