Ayyalusamy Ramamoorthy
Encyclopedia
Ayyalusamy Ramamoorthy is a professor of biophysics
at the University of Michigan, Ann Arbor. He received a Ph.D. in chemistry from the Indian Institute of Technology, Kanpur in 1990. He is graduated in Chemistry of 1984 batch from V.O.C. Arts & Science College
, Tuticorin, Tamil Nadu
, His main area of research is the development of solid-state NMR
and its applications to non-soluble, non-crystalline chemical and biological solids. He is known for the development of solid-state NMR methods (such as USEME, PISEMA, PITANSEMA, HIMSELF, etc.) and as a researcher of membrane-associated peptides and proteins, an organizer of international symposia, and author of a book on NMR Spectroscopy
of biological solid
s. He was also involved in the characterization of new nanomaterials. He teaches Chemistry, Biophysics and NMR to undergraduate and graduate students at the University of Michigan.
Biophysics
Biophysics is an interdisciplinary science that uses the methods of physical science to study biological systems. Studies included under the branches of biophysics span all levels of biological organization, from the molecular scale to whole organisms and ecosystems...
at the University of Michigan, Ann Arbor. He received a Ph.D. in chemistry from the Indian Institute of Technology, Kanpur in 1990. He is graduated in Chemistry of 1984 batch from V.O.C. Arts & Science College
V.O.C. Arts & Science College
V. O. Chidambaram College is a college of arts and sciences in Tuticorin, , a southern city of Tamil Nadu, India. The college offers undergraduate courses, postgraduate courses, and research courses...
, Tuticorin, Tamil Nadu
Tamil Nadu
Tamil Nadu is one of the 28 states of India. Its capital and largest city is Chennai. Tamil Nadu lies in the southernmost part of the Indian Peninsula and is bordered by the union territory of Pondicherry, and the states of Kerala, Karnataka, and Andhra Pradesh...
, His main area of research is the development of solid-state NMR
NMR
NMR may refer to:Applications of Nuclear Magnetic Resonance:* Nuclear magnetic resonance* NMR spectroscopy* Solid-state nuclear magnetic resonance* Protein nuclear magnetic resonance spectroscopy* Proton NMR* Carbon-13 NMR...
and its applications to non-soluble, non-crystalline chemical and biological solids. He is known for the development of solid-state NMR methods (such as USEME, PISEMA, PITANSEMA, HIMSELF, etc.) and as a researcher of membrane-associated peptides and proteins, an organizer of international symposia, and author of a book on NMR Spectroscopy
NMR spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy, is a research technique that exploits the magnetic properties of certain atomic nuclei to determine physical and chemical properties of atoms or the molecules in which they are contained...
of biological solid
Solid
Solid is one of the three classical states of matter . It is characterized by structural rigidity and resistance to changes of shape or volume. Unlike a liquid, a solid object does not flow to take on the shape of its container, nor does it expand to fill the entire volume available to it like a...
s. He was also involved in the characterization of new nanomaterials. He teaches Chemistry, Biophysics and NMR to undergraduate and graduate students at the University of Michigan.
His books
- NMR Spectroscopy of Biological Solids, 2005, Publisher: CRC PressCRC PressThe CRC Press, LLC is a publishing group which specializes in producing technical books. While many of their books relate to engineering, science and mathematics, their scope also includes books on business, forensics and information technology...
, ISBN 1-57444-496-4 - Thermotropic Liquid Crystals: Recent Advances (editor), 2007, Publisher: Springer; ISBN 1-4020-5327-4
Key publications
- http://www.ncbi.nlm.nih.gov/pubmed/18444645?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSumBrender JR, Lee EL, Cavitt MA, Gafni A, Steel DG, Ramamoorthy A. Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide. J. Am. Chem. Soc. 130 (2008) 6424–6429.]
- Xu J, Struppe J, Ramamoorthy A. Two-dimensional homonuclear chemical shift correlation established by the cross-relaxation driven spin diffusion in solids. J. Chem. Phys. 128 (2008) 052308.
- Dürr UHN, Yamamoto K, Im SC, Waskell L, Ramamoorthy A, Solid-State NMR Reveals Structural and Dynamical Properties of a Membrane-Anchored Electron-Carrier Protein, Cytochrome b(5), J. Am. Chem. Soc. 129 (2007) 6670-6671.
- Dürr UHN, Waskell L, Ramamoorthy A. The cytochromes P450 and b5 and their reductases-Promising targets for structural studies by advanced solid-state NMR spectroscopy, Biochim. Biophys. Acta. 1768 (2007) 3235-3259.
- Podsiadlo P, Kaushik AK, Arruda EM, Waas AM, Sup B, Shim, Xu J, Nandivada H, Pumplin BG, Lahann J, Ramamoorthy A, Kotov NA, Ultrastrong and Stiff Layered Polymer Nanocomposites, Science. 318 (2007) 80-83.
- Dürr UHN, Sudheendra US, Ramamoorthy A, LL-37, the only human member of the cathelicidin family of antimicrobial peptides, Biochim. Biophys. Acta 1758 (2006) 1408-1425.
- Dhople V, Krukemeyer A, Ramamoorthy A, The human beta-defensin-3, an antibacterial peptide with multiple biological functions, Biochim. Biophys. Acta 1758 (2006) 1499-1512.
- Dvinskikh SV, Durr U, Yamamoto K, Ramamoorthy A, A high-resolution solid-state NMR approach for the structural studies of bicelles, J. Am. Chem. Soc. 128 (2006) 6326-7.