APC internal ribosome entry site (IRES)
Encyclopedia
The APC internal ribosome entry site (IRES) is an RNA
element which is located in the coding sequence of the APC gene
. APC is a tumour suppressor gene which is associated with the inherited disease
adenomatous polyposis
coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
element which is located in the coding sequence of the APC gene
APC (gene)
Adenomatous polyposis coli also known as deleted in polyposis 2.5 is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer....
. APC is a tumour suppressor gene which is associated with the inherited disease
Disease
A disease is an abnormal condition affecting the body of an organism. It is often construed to be a medical condition associated with specific symptoms and signs. It may be caused by external factors, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune...
adenomatous polyposis
Familial adenomatous polyposis
Familial adenomatous polyposis is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when not treated....
coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.