4-hydroxybenzoate nonaprenyltransferase
Encyclopedia
In enzymology, a 4-hydroxybenzoate nonaprenyltransferase is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that catalyzes
Catalysis
Catalysis is the change in rate of a chemical reaction due to the participation of a substance called a catalyst. Unlike other reagents that participate in the chemical reaction, a catalyst is not consumed by the reaction itself. A catalyst may participate in multiple chemical transformations....

 the chemical reaction
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...


solanesyl diphosphate (nonaisoprenol diphosphate) + 4-hydroxybenzoate diphosphate + nonaprenyl-4-hydroxybenzoate


Thus, the two substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...

 of this enzyme are nonaisoprenol diphosphate and 4-hydroxybenzoate, whereas its two products
Product (chemistry)
Product are formed during chemical reactions as reagents are consumed. Products have lower energy than the reagents and are produced during the reaction according to the second law of thermodynamics. The released energy comes from changes in chemical bonds between atoms in reagent molecules and...

 are diphosphate and nonaprenyl-4-hydroxybenzoate.

This enzyme belongs to the family of transferase
Transferase
In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another . For example, an enzyme that catalyzed this reaction would be a transferase:In this example, A would be the donor, and B would be the acceptor...

s, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in ubiquinone biosynthesis
Biosynthesis
Biosynthesis is an enzyme-catalyzed process in cells of living organisms by which substrates are converted to more complex products. The biosynthesis process often consists of several enzymatic steps in which the product of one step is used as substrate in the following step...

.

Nomenclature

The systematic name of this enzyme class is solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase. Other names in common use include:
  • nonaprenyl-4-hydroxybenzoate transferase,
  • 4-hydroxybenzoate transferase,
  • p-hydroxybenzoate dimethylallyltransferase,
  • p-hydroxybenzoate polyprenyltransferase,
  • p-hydroxybenzoic acid-polyprenyl transferase, and
  • p-hydroxybenzoic-polyprenyl transferase.
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