(R)-3-Nitrobiphenyline
Encyclopedia
-3-Nitrobiphenyline is a drug which acts as an α2-adrenergic
agonist
, selective for the α2C
subtype, as well as being a weak antagonist at the α2A and α2B subtypes.
Alpha-2 adrenergic receptor
The alpha-2 adrenergic receptor is a G protein-coupled receptor associated with the Gi heterotrimeric G-protein. It consists of three highly homologous subtypes, including α2A-, α2B-, and α2C-adrenergic. Some species other than humans express a fourth α2D-adrenergic receptor as well...
agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
, selective for the α2C
Alpha-2C adrenergic receptor
The alpha-2C adrenergic receptor , also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it.-Agonists:* -3-Nitrobiphenyline -Antagonists:...
subtype, as well as being a weak antagonist at the α2A and α2B subtypes.