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Wohl-Aue reaction

Wohl-Aue reaction

Overview
The Wohl-Aue reaction is an organic reaction
Organic reaction
Organic reactions are chemical reactions involving organic compounds. The basic organic chemistry reaction types are addition reactions, elimination reactions, substitution reactions, pericyclic reactions, rearrangement reactions and redox reactions. In organic synthesis, organic reactions are used...

 between an aromatic nitro compound
Nitro compound
Nitro compounds are organic compounds that contain one or more nitro functional groups . They are often highly explosive, especially when the compound contains more than one nitro group. The presence of impurities or improper handling can trigger a violent exothermic decomposition...

 and an aniline
Aniline
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...

 to form a phenazine
Phenazine
Phenazine , also called azophenylene, dibenzo-p-diazine, dibenzopyrazine, and acridizine, is a dibenzo annulated pyrazine and the parent substance of many dyestuffs, such as the eurhodines, toluylene red, indulines and safranines.-Synthesis:A classic...

 in presence of an alkali base
Alkali
In chemistry, an alkali is a basic, ionic salt of an alkali metal or alkaline earth metal element. Alkalis are best known for being bases that dissolve in water. Bases are compounds with a pH greater than 7. The adjective alkaline is commonly used in English as a synonym for base, especially for...

. An example is the reaction between nitrobenzene
Nitrobenzene
Nitrobenzene is an organic compound with the chemical formula C6H5NO2. Nitrobenzene is a water-insoluble pale yellow oil with an almond-like odor. It freezes to give greenish-yellow crystals. Although occasionally used as a flavoring or perfume additive,...

 and aniline
Aniline
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...

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Encyclopedia
The Wohl-Aue reaction is an organic reaction
Organic reaction
Organic reactions are chemical reactions involving organic compounds. The basic organic chemistry reaction types are addition reactions, elimination reactions, substitution reactions, pericyclic reactions, rearrangement reactions and redox reactions. In organic synthesis, organic reactions are used...

 between an aromatic nitro compound
Nitro compound
Nitro compounds are organic compounds that contain one or more nitro functional groups . They are often highly explosive, especially when the compound contains more than one nitro group. The presence of impurities or improper handling can trigger a violent exothermic decomposition...

 and an aniline
Aniline
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...

 to form a phenazine
Phenazine
Phenazine , also called azophenylene, dibenzo-p-diazine, dibenzopyrazine, and acridizine, is a dibenzo annulated pyrazine and the parent substance of many dyestuffs, such as the eurhodines, toluylene red, indulines and safranines.-Synthesis:A classic...

 in presence of an alkali base
Alkali
In chemistry, an alkali is a basic, ionic salt of an alkali metal or alkaline earth metal element. Alkalis are best known for being bases that dissolve in water. Bases are compounds with a pH greater than 7. The adjective alkaline is commonly used in English as a synonym for base, especially for...

. An example is the reaction between nitrobenzene
Nitrobenzene
Nitrobenzene is an organic compound with the chemical formula C6H5NO2. Nitrobenzene is a water-insoluble pale yellow oil with an almond-like odor. It freezes to give greenish-yellow crystals. Although occasionally used as a flavoring or perfume additive,...

 and aniline
Aniline
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...

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The reaction is named after Alfred Wohl
Alfred Wohl
Alfred Wohl 3 October 1863 – 25 December 1946) was a German chemist.Several chemical reactions are named after him, like the Wohl degradation , Wohl-Aue reaction and the Wohl-Ziegler reaction -Life and Work:...

and W. Aue.