The
Wohl-Aue reaction is an
organic reactionOrganic reactions are chemical reactions involving organic compounds. The basic organic chemistry reaction types are addition reactions, elimination reactions, substitution reactions, pericyclic reactions, rearrangement reactions and redox reactions. In organic synthesis, organic reactions are used...
between an aromatic
nitro compoundNitro compounds are organic compounds that contain one or more nitro functional groups . They are often highly explosive, especially when the compound contains more than one nitro group. The presence of impurities or improper handling can trigger a violent exothermic decomposition...
and an
anilineAniline, phenylamine or aminobenzene is an organic compound with the formula C
6H
7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...
to form a
phenazinePhenazine , also called azophenylene, dibenzo-p-diazine, dibenzopyrazine, and acridizine, is a dibenzo annulated pyrazine and the parent substance of many dyestuffs, such as the eurhodines, toluylene red, indulines and safranines.-Synthesis:A classic...
in presence of an
alkali baseIn chemistry, an alkali is a basic, ionic salt of an alkali metal or alkaline earth metal element. Alkalis are best known for being bases that dissolve in water. Bases are compounds with a pH greater than 7. The adjective alkaline is commonly used in English as a synonym for base, especially for...
. An example is the reaction between
nitrobenzeneNitrobenzene is an organic compound with the chemical formula C
6H
5NO
2. Nitrobenzene is a water-insoluble pale yellow oil with an almond-like odor. It freezes to give greenish-yellow crystals. Although occasionally used as a flavoring or perfume additive,...
and
anilineAniline, phenylamine or aminobenzene is an organic compound with the formula C
6H
7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...
:
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The
Wohl-Aue reaction is an
organic reactionOrganic reactions are chemical reactions involving organic compounds. The basic organic chemistry reaction types are addition reactions, elimination reactions, substitution reactions, pericyclic reactions, rearrangement reactions and redox reactions. In organic synthesis, organic reactions are used...
between an aromatic
nitro compoundNitro compounds are organic compounds that contain one or more nitro functional groups . They are often highly explosive, especially when the compound contains more than one nitro group. The presence of impurities or improper handling can trigger a violent exothermic decomposition...
and an
anilineAniline, phenylamine or aminobenzene is an organic compound with the formula C
6H
7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...
to form a
phenazinePhenazine , also called azophenylene, dibenzo-p-diazine, dibenzopyrazine, and acridizine, is a dibenzo annulated pyrazine and the parent substance of many dyestuffs, such as the eurhodines, toluylene red, indulines and safranines.-Synthesis:A classic...
in presence of an
alkali baseIn chemistry, an alkali is a basic, ionic salt of an alkali metal or alkaline earth metal element. Alkalis are best known for being bases that dissolve in water. Bases are compounds with a pH greater than 7. The adjective alkaline is commonly used in English as a synonym for base, especially for...
. An example is the reaction between
nitrobenzeneNitrobenzene is an organic compound with the chemical formula C
6H
5NO
2. Nitrobenzene is a water-insoluble pale yellow oil with an almond-like odor. It freezes to give greenish-yellow crystals. Although occasionally used as a flavoring or perfume additive,...
and
anilineAniline, phenylamine or aminobenzene is an organic compound with the formula C
6H
7N. It is the simplest and one of the most important aromatic amines, being used as a precursor to more complex chemicals. Its main application is in the manufacture of polyurethane...
:
The reaction is named after
Alfred WohlAlfred Wohl 3 October 1863 – 25 December 1946) was a German chemist.Several chemical reactions are named after him, like the Wohl degradation , Wohl-Aue reaction and the Wohl-Ziegler reaction -Life and Work:...
and W. Aue.