Wogonin
Encyclopedia
Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which was found in Scutellaria baicalensis
Scutellaria baicalensis
Scutellaria baicalensis is a species of flowering plant in the Lamiaceae family.-Medicinal uses:...


The glycoside
Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to a non-carbohydrate moiety, usually a small organic molecule. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme...

s of wogonin are known as wogonosides. For example, oroxindin
Oroxindin
Oroxindin is a chemical compound. It is a wogonoside, more accurately a wogonin glucuronide isolated from Oroxylum indicum , Bacopa monnieri and Holmskioldia sanguinea ....

 is a wogonin glucuronide
Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond...

 isolated from Oroxylum indicum
Oroxylum indicum
Oroxylum indicum is a species of flowering plant belonging to the family Bignoniaceae.-Names:* Bignonia indica, L., Species Plantarum 2: 625. 1753.* Spathodea indica, L., Pers. Synopsis Plantarum 2: 173. 1807....

. It is one of the active ingredients of Sho-Saiko-To
Sho-saiko-to
Sho-Saiko-To , also known as Minor Bupleurum Formula and Xiao Chai Hu Tang in Chinese, is a herbal supplement, believed to enhance liver health. Sho-Saiko-To is a widely used prescription drug in Japan and is a listed formula in Japanese Kampo. There are currently ongoing clinical trials for...

, a Japanese herbal supplement believed to enhance liver health.

Wogonin has been found in one study to have anxiolytic
Anxiolytic
An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...

properties in mice at doses of 7.5 to 30 mg/kg, without exhibiting the sedative and muscle-relaxing properties of benzodiazepines.
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