VISA (gene)
Encyclopedia
Mitochondrial antiviral-signaling protein (MAVS) is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the MAVS gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

. The protein is also known by the names VISA, IPS-1 and Cardif. Aggregated MAVS form protease resistant prion-like aggregates that activate IRF3
IRF3
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor.- Function :IRF3 is a member of the interferon regulatory transcription factor family. IRF3 was originally discovered as a homolog of IRF1 and IRF2...

dimerization.

NCBI Refseq summary of MAVS

Further reading

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