Urine organic acids
Encyclopedia
Urine organic acids is a medical diagnostic test used to exclude the possibility that a person has an inborn error of metabolism
, usually one of the organic acidemias. The usual method of analysis is tandem mass spectrometry
. In most cases a random specimen of as little as 1-5 ml is enough for analysis.
Inborn error of metabolism
Inborn errors of metabolism comprise a large class of genetic diseases involving disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances into others...
, usually one of the organic acidemias. The usual method of analysis is tandem mass spectrometry
Tandem mass spectrometry
Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages.-Tandem MS instruments:...
. In most cases a random specimen of as little as 1-5 ml is enough for analysis.