Trisomy 16
Encyclopedia
Trisomy 16 is a chromosomal abnormality in which there are three copies of chromosome 16
rather than two. It is the most common chromosomal cause of miscarriage
during the first trimester of pregnancy
.
It is not possible for a child to be born alive with an extra copy of this chromosome present in all cells (called Full Trisomy 16).
It is possible for a child to be born alive with the mosaic
form.
Chromosome 16 (human)
125px|rightChromosome 16 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 16 spans about 90 million base pairs and represents just under 3 % of the total DNA in cells.Identifying genes on each chromosome is an active area of genetic...
rather than two. It is the most common chromosomal cause of miscarriage
Miscarriage
Miscarriage or spontaneous abortion is the spontaneous end of a pregnancy at a stage where the embryo or fetus is incapable of surviving independently, generally defined in humans at prior to 20 weeks of gestation...
during the first trimester of pregnancy
Pregnancy
Pregnancy refers to the fertilization and development of one or more offspring, known as a fetus or embryo, in a woman's uterus. In a pregnancy, there can be multiple gestations, as in the case of twins or triplets...
.
It is not possible for a child to be born alive with an extra copy of this chromosome present in all cells (called Full Trisomy 16).
It is possible for a child to be born alive with the mosaic
Mosaic (genetics)
In genetic medicine, a mosaic or mosaicism denotes the presence of two populations of cells with different genotypes in one individual who has developed from a single fertilized egg...
form.