The Edwards brothers, Fisher, and Hogben
Encyclopedia
The brothers John H.
John H. Edwards
John Hilton Edwards was a British medical geneticist. Edwards reported the first description of a syndrome of multiple congenital malformations associated the presence of an extra chromosome. The extra chromosome belonged to the E group of chromosomes which consisted of chromosomes 16, 17 and 18...

 and A.W.F. Edwards, and their respective mentors Lancelot Hogben
Lancelot Hogben
Lancelot Thomas Hogben FRS was a versatile British experimental zoologist and medical statistician. He is best known for developing Xenopus laevis as a model organism for biological research in his early career, attacking the eugenics movement in the middle of his career, and popularising books on...

 and Ronald Fisher
Ronald Fisher
Sir Ronald Aylmer Fisher FRS was an English statistician, evolutionary biologist, eugenicist and geneticist. Among other things, Fisher is well known for his contributions to statistics by creating Fisher's exact test and Fisher's equation...

, were scientists in the 20th century. The two senior researchers developed opposing theories on the genotype-environment interaction (called G × E); the elder brother, John, came to be known as "Hogben's Edwards
John H. Edwards
John Hilton Edwards was a British medical geneticist. Edwards reported the first description of a syndrome of multiple congenital malformations associated the presence of an extra chromosome. The extra chromosome belonged to the E group of chromosomes which consisted of chromosomes 16, 17 and 18...

", and A.W.F. as "Fisher's Edwards".
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