Anatomical boundaries

The sublingual space is a space between the mylohyoid muscle

Mylohyoid muscle

The mylohyoid muscle is a muscle running from the mandible to the hyoid bone, forming the floor of the oral cavity. It is named for its two attachments, with the prefix "mylo" coming from the Greek word for "molar". These muscles are mesodermal in origin...

 and the geniohyoid and genioglossal muscles, containing a number of vessels and nerves, such as the lingual artery

Lingual artery

The lingual artery arises from the external carotid between the superior thyroid and facial artery. It can be located easily in the tongue.-Path:It first runs obliquely upward and medialward to the greater cornu of the hyoid bone....

 and nerve, and the hypoglossal and glossopharyngeal nerve

Glossopharyngeal nerve

The glossopharyngeal nerve is the ninth of twelve pairs of cranial nerves . It exits the brainstem out from the sides of the upper medulla, just rostral to the vagus nerve...

, Wharton's duct and some extrinsic tongue muscle fibers. The sublingual space also contains the sublingual salivary gland. Secretions from the sublingual gland drain through several small excretory ducts in the floor of the mouth; sometimes a more distinctive duct can be recognized, known as Bartholin's duct

Bartholin's duct

Bartholin's ducts are a pair of ducts leading from the Bartholin's glands to the surface of the vulva.It is claimed that the two external openings of the Bartholin's ducts are often invisible to the naked human eye....

.

Pathology

Pathology arising from the sublingual gland is rare; however, sublingual gland neoplasms are predominantly malignant and thus important to recognize.
People suffering from Ludwig's angina, cellulitis in the floor of the mouth, will commonly have the infection spread to the sublingual space. The submental and submandibular spaces will also be affected by this infection.