Streptolysin
Encyclopedia
Streptolysin is a streptococcal hemolytic exotoxin
Exotoxin
An exotoxin is a toxin excreted by a microorganism, like bacteria, fungi, algae, and protozoa. An exotoxin can cause damage to the host by destroying cells or disrupting normal cellular metabolism. They are highly potent and can cause major damage to the host...

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Types include Streptolysin O (SLO), which is oxygen-labile, and Streptolysin S (SLS), which is oxygen-stable.

An antibody, anti-streptolysin O
Anti-streptolysin O
Anti-streptolysin O is the antibody made against streptolysin O, an immunogenic, oxygen-liable hemolytic toxin produced by most strains of group A and many strains of groups C and G streptococci. The O in the name stands for oxygen-labile; the other related toxin being oxygen-stable streptolysin-S...

, can be detected in an antistreptolysin O titre.

Streptolysin O is hemolytically active only in a reversibly reduced state unlike Streptolysin S which is stable in the presence of oxygen. Another difference is that that slo is antigenic while sls is non antigenic due to its small size.
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