Splenic lymphoid nodules
Encyclopedia
White pulp is a histological region of the spleen
Spleen
The spleen is an organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve of blood in case of hemorrhagic shock...

. The altered coat of the arterioles, consisting of adenoid
Adenoid
Adenoids are a mass of lymphoid tissue situated posterior to the nasal cavity, in the roof of the nasopharynx, where the nose blends into the throat....

 tissue, presents here and there thickenings of a spheroidal shape, the white pulp (Malpighian bodies of the spleen, splenic lymphoid nodules).

These bodies vary in size from about 0.25 mm. to 1 mm. in diameter.

They are merely local expansions or hyperplasia
Hyperplasia
Hyperplasia means increase in number of cells/proliferation of cells. It may result in the gross enlargement of an organ and the term is sometimes mixed with benign neoplasia/ benign tumor....

 of the adenoid tissue, of which the external coat of the smaller arteries of the spleen
Spleen
The spleen is an organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve of blood in case of hemorrhagic shock...

 is formed.

They are most frequently found surrounding the arteriole
Arteriole
An arteriole is a small diameter blood vessel in the microcirculation that extends and branches out from an artery and leads to capillaries.Arterioles have muscular walls and are the primary site of vascular resistance...

, which thus seems to tunnel them, but occasionally they grow from one side of the vessel only, and present the appearance of a sessile bud growing from the arterial wall.

Typically associated with the arteriole supply of the spleen; forming what are called periarterial lymphatic sheaths (PALS).
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