U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets. U24 is encoded within an intron of the gene for ribosomal protein L7a

Ribosomal protein

A ribosomal protein is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular process of translation. A large part of the knowledge about these organic molecules has come from the study of E. coli ribosomes. Most ribosomic proteins have been...

 in mammals, chicken and Fugu. The U76/SNORD76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene. snoRNAs Z20 and U76 snoRNAs show clear similarity to U24.

An experiment that looked at 22 different non-small-cell lung cancer

Lung cancer

Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary...

 tissues found that SNORD33

Small nucleolar RNA Z195/SNORD33 family

Small nucleolar RNA Z195/SNORD33 is a non-coding RNA molecule which functions in the modification of other small nuclear RNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

, SNORD66

Small nucleolar RNA SNORD66

SNORD66 is a non-coding RNA molecule which functions in the modification of other small nuclear RNAs . This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis...

and SNORD76 were over-expressed relative to matched noncancerous lung tissues.