Skin equivalent
Encyclopedia
A skin equivalent is an in vitro skin model using to conduct experiments on processes involving the skin, such as wound healing and keratinocyte
migration. It is a more complex form of the dermal equivalent
.
Keratinocyte
Keratinocytes are the predominant cell type in the epidermis, the outermost layer of the human skin, constituting 95% of the cells found there. Those keratinocytes found in the basal layer of the skin are sometimes referred to as "basal cells" or "basal keratinocytes"...
migration. It is a more complex form of the dermal equivalent
Dermal equivalent
The dermal equivalent is an in vitro model of the dermal layer of skin. It is constructed by seeding dermal fibroblasts into a collagen gel. This gel may then be allowed to contract as a model of wound contraction. This collagen gel contraction assay may be used to screen for treatments which...
.