SF1 (gene)
Encyclopedia
Splicing factor 1 also known as zinc finger protein 162 (ZFM162) is a protein
that in humans is encoded by the SF1 gene
.
Splicing factor SF1 is involved in the ATP-dependent formation of the spliceosome
complex.
with Ewing sarcoma breakpoint region 1
, U2AF2
and Transcription elongation regulator 1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the SF1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Splicing factor SF1 is involved in the ATP-dependent formation of the spliceosome
Spliceosome
A spliceosome is a complex of snRNA and protein subunits that removes introns from a transcribed pre-mRNA segment. This process is generally referred to as splicing.-Composition:...
complex.
Interactions
SF1 (gene) has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Ewing sarcoma breakpoint region 1
Ewing sarcoma breakpoint region 1
RNA-binding protein EWS is a protein that in humans is encoded by the EWSR1 gene.-Interactions:Ewing sarcoma breakpoint region 1 has been shown to interact with POU4F1, SF1, BARD1, Small nuclear ribonucleoprotein polypeptide C, PTK2B and Zinc finger protein 165.ERG, ATF-1,-External links:* on the...
, U2AF2
U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.-Interactions:U2AF2 has been shown to interact with WT1, PUF60, SFRS2IP, SRPK2, SF1, U2 small nuclear RNA auxiliary factor 1 and SFRS11.-References:...
and Transcription elongation regulator 1
Transcription elongation regulator 1
Transcription elongation regulator 1, also known as TCERG1, is a protein which in humans is encoded by the TCERG1 gene.- Function :This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing...
.