Primary mediastinal B-cell lymphoma
Encyclopedia
Primary mediastinal B-cell lymphoma, abbreviated PMBL, is a type of lymphoma
Lymphoma
Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...

 that rises in the mediastinum
Mediastinum
The mediastinum is a non-delineated group of structures in the thorax, surrounded by loose connective tissue. It is the central compartment of the thoracic cavity...

 and predominantly affects young adults.

It is similar to diffuse large B-cell lymphoma; however, generally has a significantly better prognosis.

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