Polar T3 syndrome
Encyclopedia
Polar T3 syndrome is a condition found in polar explorers, caused by a reduction in levels of the thyroid hormone
Thyroid hormone
The thyroid hormones, thyroxine and triiodothyronine , are tyrosine-based hormones produced by the thyroid gland primarily responsible for regulation of metabolism. An important component in the synthesis of thyroid hormones is iodine. The major form of thyroid hormone in the blood is thyroxine ,...

 T3
Triiodothyronine
Triiodothyronine, C15H12I3NO4, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate....

. Its effects include forgetfulness, cognitive impairment and mood disturbances. It can exhibit itself in a fugue state
Fugue state
A fugue state, formally dissociative fugue or psychogenic fugue , is a rare psychiatric disorder characterized by reversible amnesia for personal identity, including the memories, personality and other identifying characteristics of individuality...

 known as the "Antarctic stare".

It is regarded as one of the contributory causes of winter-over syndrome
Winter-over syndrome
The winter-over syndrome is observed in inhabitants of research stations in Antarctica who "winter-over" throughout the Antarctic winter. It consists of a variety of behavioral and medical disturbances, including irritability...

.
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