Phosphoribosylamine
Encyclopedia
Phosphoribosylamine is an intermediate in purine metabolism
. It is a precursor to IMP. It is generated from Phosphoribosyl pyrophosphate
(PRPP).
Purine metabolism
-Biosynthesis:Purines are biologically synthesized as nucleotides and in particular as ribotides, i.e. bases attached to ribose 5-phosphate. A key regulatory step is the production of 5-phospho-α-D-ribosyl 1-pyrophosphate by PRPP synthetase, which is activated by inorganic phosphate and...
. It is a precursor to IMP. It is generated from Phosphoribosyl pyrophosphate
Phosphoribosyl pyrophosphate
Phosphoribosyl pyrophosphate is a pentosephosphate.It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase.It plays a role in transferring phospho-ribose groups in several reactions:...
(PRPP).
See also
- AmidophosphoribosyltransferaseAmidophosphoribosyltransferaseAmidophosphoribosyltransferase , also known as glutamine phosphoribosylpyrophosphate amidotransferase , is an enzyme that in humans is encoded by the PPAT gene.- Function :...
- Phosphoribosyl pyrophosphatePhosphoribosyl pyrophosphatePhosphoribosyl pyrophosphate is a pentosephosphate.It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase.It plays a role in transferring phospho-ribose groups in several reactions:...