PF-184563
Encyclopedia
PF-184563 is a potent, selective non-peptidic antagonist of the V1a receptor
Arginine vasopressin receptor 1A
Arginine vasopressin receptor 1A is one of the three major receptor types for arginine vasopressin , and is present throughout the brain, as well as in the periphery in the liver, kidney, and vasculature.Arginine vasopressin receptor 1A is also known as:* V1a vasopressin receptor* antidiuretic...

.. The compound was discovered by Pfizer
Pfizer
Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States...

 in its Sandwich, Kent
Sandwich, Kent
Sandwich is a historic town and civil parish on the River Stour in the Non-metropolitan district of Dover, within the ceremonial county of Kent, south-east England. It has a population of 6,800....

 research center, as a potential treatment for dysmenorrhoea, an indication for which V1a antagonists have shown efficacy..
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