Optical projection tomography
Encyclopedia
Optical projection tomography is a form of tomography
involving optical microscopy.
It is in many ways the optical equivalent of X-Ray Computed Tomography or the medical CT scan. OPT differs in the way that it assumes parallel ray projection as opposed to fan beam projection as is the case for X-ray CT. The technique has already contributed to a large number of studies aimed at addressing a broad range of biological questions in diverse systems such as human, mice, chicken, fly, zebrafish and plants. More recent adaptations have further enabled the use of the technique for studies of specimen on the adult mouse organ scale, individual cell nuclei and for longitudinal assessments of organ cultures.
Tomography
Tomography refers to imaging by sections or sectioning, through the use of any kind of penetrating wave. A device used in tomography is called a tomograph, while the image produced is a tomogram. The method is used in radiology, archaeology, biology, geophysics, oceanography, materials science,...
involving optical microscopy.
It is in many ways the optical equivalent of X-Ray Computed Tomography or the medical CT scan. OPT differs in the way that it assumes parallel ray projection as opposed to fan beam projection as is the case for X-ray CT. The technique has already contributed to a large number of studies aimed at addressing a broad range of biological questions in diverse systems such as human, mice, chicken, fly, zebrafish and plants. More recent adaptations have further enabled the use of the technique for studies of specimen on the adult mouse organ scale, individual cell nuclei and for longitudinal assessments of organ cultures.
External links
- http://genex.hgu.mrc.ac.uk/OPT_Microscopy/optwebsite/frontpage/index.htm
- Video I: Optical Projection Tomography of a mouse left lateral liver lobe.
- Video II: Optical Projection Tomography of an embryonic stomach, intestine and pancreas of a mouse.