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Nicotinic acids are derivatives of
pyridinePyridine is a simple aromatic heterocyclic organic compound with the chemical formula C
5H
5N used as a precursor to agrochemicals and pharmaceuticals, and is also an important solvent and reagent. It is structurally related to benzene, wherein one CH group in the aromatic...
which have a substituted carboxy group.
Although the term
niacinNiacin, also known as vitamin B
3 or nicotinic acid, is a water-soluble vitamin. It is an organic compound with the molecular formula C
6H
5NO
2. It is a derivative of pyridine, with a carboxyl group at the 3-position...
is sometimes used interchangeably with "nicotinic acid", it is more precise to only apply it to the 1-3 (meta) substituted form.
Examples include:
- arecoline
Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm . It is an odourless oily liquid volatile in steam, miscible with most organic solvents and water, but extractable from the latter by ether in presence of dissolved salts. The salts are crystalline, but...
- nicotinamide
Nicotinamide, also known as niacinamide and nicotinic acid amide, is the amide of nicotinic acid . Nicotinamide is a water-soluble vitamin and is part of the vitamin B group...
- nicorandil
Nicorandil is a vasodilatory drug used to treat angina. It is marketed under the trade names Ikorel , Dancor , Nikoran , Aprior and Sigmart...
- nikethamide
Nikethamide is a stimulant which mainly affects the respiratory cycle. Widely known by its former trade name of Coramine, it was used in the mid-1900s as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion...
- nimodipine
Nimodipine is a dihydropyridine calcium channel blocker originally developed for the treatment of high blood pressure...