National Highway 2 is a south-north flowing highway of central-western Burma.

The highway begins at Satthwadaw, to the north of Yangon

Yangon

Yangon is a former capital of Burma and the capital of Yangon Region . Although the military government has officially relocated the capital to Naypyidaw since March 2006, Yangon, with a population of over four million, continues to be the country's largest city and the most important commercial...

 at 17°2′30"N 96°7′56"E where it is fed by the National Highway 1

National Highway 1 (Burma)

National Highway 1 , literally "The Road to Mandalay ") is an important south-north flowing highway of central Burma and the busiest road in the country...

 and then branches off to the northwest. At Myingyan

Myingyan

Myingyan is a city and district in the Mandalay Division of central Myanmar, previously, it was a district in the Meiktila Division of Upper Burma. It is currently the capital of Myingyan Township and lies along the National Highway 2. , the city had a population of 123,700 and the district had...

 it joins the National Road 18. At this point the road forks to the east and eventually rejoins National Highway 1 near the village of Gyobinchan in Myittha Township

Myittha Township

Myittha Township is a township of Kyaukse District in the Mandalay Division of Burma. The capital is Myittha. Myittha Township consists of 6 wards, 227 villages....

 at 21°22′59"N 96°10′32"E. The highway mostly follows the course of the Ayeyarwady River

Ayeyarwady River

The Irrawaddy River or Ayeyarwady River is a river that flows from north to south through Burma . It is the country's largest river and most important commercial waterway. Originating from the confluence of the N'mai and Mali rivers, it flows relatively straight North-South before emptying through...

on its eastern bank.