Shaikh Muhammad bin Ali bin Abdullah bin Jassim bin Muhammed Al Thani was born in 1922. He married one of his wives a daughter of Shaikh Muhammad bin Saqr al-Qasimi (the emir of Sharjah) from UAE.

He died in December 1970 at age of 48.

His first wife is sheikha Moza bint Hassan bin Abdualla bin Jassim Althani second wife is sheikha Safia Alrabban and the third wife is a daughter of Shaikh Muhammad bin Saqr al-Qasimi from UAE.

Sons

• Khalid Bin Muhammed, Died Young
• Abulrahman Bin Muhammed, Died 1968, Two Sons
• Khalid Bin Muhammed Bin Ali, Married Four Sons
• Hamad Bin Muhammed, Died 1972
• Abdulaziz Bin Muhammed, Died 1972
• Saud Bin Muhammed, Died Young
• Abdullah Bin Muhammed, Married Six Sons
• Hasan Bin Muhammed, Married Two Sons
• Nasser Bin Muhammed, Married Four Sons
• Talal Bin Muhammed, Died 1987
• Saud bin Muhammed Al Thani, Married One Son