Mre11-Rad50-Xrs2
Encyclopedia
The MRX complex is a heterotrimeric protein complex
consisting of Mre11
, Rad50
, and Xrs2. It is a budding yeast homolog of the mammalian Mre11-Rad50-Nbs1 (MRN)
DNA damage repair complex.
Protein complex
A multiprotein complex is a group of two or more associated polypeptide chains. If the different polypeptide chains contain different protein domain, the resulting multiprotein complex can have multiple catalytic functions...
consisting of Mre11
MRE11A
Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene.-Interactions:MRE11A has been shown to interact with Ku70, Ataxia telangiectasia mutated, MDC1, Rad50, Nibrin, TERF2 and BRCA1.-Further reading:...
, Rad50
RAD50
Rad50 may refer to:* RADIX-50, a character encoding scheme in computing* RAD50 , in biology, encodes a DNA repair protein involved in DNA double-strand break repair...
, and Xrs2. It is a budding yeast homolog of the mammalian Mre11-Rad50-Nbs1 (MRN)
Mre11-Rad50-Nbs1
The MRN complex is heterotrimeric protein complex consisting of Mre11, Rad50 and Nbs1. It is involved in DNA repair in mammals. Nbs1 is referred to as Nibrin. This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. Its activity includes end-processing of...
DNA damage repair complex.