Mnt IRES
Encyclopedia
The Mnt internal ribosome entry site (IRES) is an RNA element
. Mnt is a transcriptional repressor related to the Myc/Mad family of transcription factor
s. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
. Mnt is a transcriptional repressor related to the Myc/Mad family of transcription factor
Transcription factor
In molecular biology and genetics, a transcription factor is a protein that binds to specific DNA sequences, thereby controlling the flow of genetic information from DNA to mRNA...
s. It is thought that this IRES allows efficient Mnt synthesis when cap-dependent translation initiation is reduced.
See also
- N-myc IRESN-myc internal ribosome entry site (IRES)The N-myc internal ribosome entry site is an RNA element found in the n-myc gene. The myc family of genes when expressed are known to be involved in the control of cell growth, differentiation and apoptosis...
- Tobamovirus IRESTobamovirus internal ribosome entry site (IRES)The Tobamovirus internal ribosome entry site is an element that allows cap and end-independent translation of mRNA in the host cell. The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and...
- TrkB IRESTrkB IRESThe TrkB internal ribosome entry site is an RNA element which is present in the 5' UTR sequence of the mRNA. TrkB is a neurotrophin receptor which is essential for the development and maintenance of the nervous system...