Matrix-Core
Encyclopedia
The Matrix-Core theory of thalamus
Thalamus
The thalamus is a midline paired symmetrical structure within the brains of vertebrates, including humans. It is situated between the cerebral cortex and midbrain, both in terms of location and neurological connections...

, first proposed by Ted Jones
Ted Jones (neuroscientist)
Edward G. Jones was a neuroscientist and a prolific neuroanatomist. One of his main contributions involves his Matrix-Core theory of thalamic organization. He authored a highly influential book entitled The Thalamus in 1985...

, states that neurons in the thalamus belong to either a calbindin-immunopositive matrix of diffusely and widely projecting neurons, or to a parvalbumin-immunopositive core of precisely projecting neurons . The neurons comprising the core are believed to be involved in propagation of 'driving' information, whereas neurons comprising the matrix are believed to play a more modulatory role.
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