MCOLN2
Encyclopedia
Mucolipin-2 also known as TRPML2 (transient receptor potential cation channel, mucolipin subfamily, member 2) is a protein
that in humans is encoded by the MCOLN2 gene
. It is a member of the small family of the TRPML
channels, a subgroup of the large protein family of TRP
ion channels.
TRPML2 is associated with the Arf6
-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the MCOLN2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. It is a member of the small family of the TRPML
TRPML
TRPML comprises a group of three evolutionary related proteins that belongs to the large family of transient receptor potential ion channels...
channels, a subgroup of the large protein family of TRP
TRP
TRP may refer to:* Trooper, Canadian military abbreviation* Tryptophan, an amino acid* The transient receptor potential channel* Time Reading Program, a book sales club run by Time Life Books in the 1960's* Thomas Ruggles Pynchon, American writer...
ion channels.
TRPML2 is associated with the Arf6
Arf6
ADP-ribosylation factor 6 is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo...
-regulated trafficking pathway and is involved in the intracellular transport of membranes and membrane proteins.
See also
- transient receptor potential cation channel, mucolipin subfamily, member 1 (MCOLN1)
- transient receptor potential cation channel, mucolipin subfamily, member 3 (MCOLN3MCOLN3Mucolipin-3 also known as TRPML3 is a protein that in humans is encoded by the MCOLN3 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.-Gene:In human, the MCOLN3 gene resides on the short arm of chromosome 1 at 1p22.3...
)
- TRPMLTRPMLTRPML comprises a group of three evolutionary related proteins that belongs to the large family of transient receptor potential ion channels...