MAD2L1
Encyclopedia
Mitotic spindle assembly checkpoint protein MAD2A is a protein
that in humans is encoded by the MAD2L1 gene
.
with MAD2L2
, CDC20
, BUB1B
, Estrogen receptor beta
, ADAM17
, UBD, CDC27
and Mad1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the MAD2L1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
MAD2L1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with MAD2L2
MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.-Interactions:MAD2L2 has been shown to interact with ADAM9, REV1, MAD2L1 and REV3L.-Further reading:...
, CDC20
CDC20
The cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex , a large 11-13 subunit complex that initiates chromatid separation...
, BUB1B
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene.-Interactions:BUB1B has been shown to interact with AP2B1, HDAC1, BUB3, MAD2L1, Gamma-synuclein, BRCA2 and CDC20.-Further reading:...
, Estrogen receptor beta
Estrogen receptor beta
Estrogen receptor beta , also known as NR3A2 , is a nuclear receptor which is activated by the sex hormone estrogen. In humans, ER-β is encoded by the ESR2 gene.- Function :...
, ADAM17
ADAM17
ADAM metallopeptidase domain 17 , also called TACE , is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases.- Chemical characteristics :...
, UBD, CDC27
CDC27
Cell division cycle protein 27 homolog is a protein that in humans is encoded by the CDC27 gene.-Interactions:CDC27 has been shown to interact with ANAPC1, ANAPC4, ANAPC5, ANAPC11, FZR1, CDC20, CDH1, CDC23, PIN1, CDC16, ANAPC7, MAD2L1 and ANAPC10....
and Mad1
Mad1
Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene.MAD1L1 is also known as Human Accelerated Region 3. It may therefore have played a key role in differentiating Humans from Apes.-Interactions:...
.