List of biotechnology companies
Encyclopedia
A biotechnology company is a company whose products or services primarily use biotechnology
methods for their production, design or delivery. Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.
Biotechnology
Biotechnology is a field of applied biology that involves the use of living organisms and bioprocesses in engineering, technology, medicine and other fields requiring bioproducts. Biotechnology also utilizes these products for manufacturing purpose...
methods for their production, design or delivery. Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.
Biotechnology companies
- The following is a list of the top 100 companies ranked by revenue (2006). The first nine companies qualify for the list of the top 50 pharmaceutical companies.
| Rank 2006 | Company | Country | Revenue in 2006 (USD millions) | R&D in 2006 (USD millions) | Net income/ (loss) in 2006 (USD millions) | Employees in 2006 |
|---|---|---|---|---|---|---|
| 1 | Amgen Amgen Amgen Inc. is an international biotechnology company headquartered in Thousand Oaks, California. Located in the Conejo Valley, Amgen is the world's largest independent biotech firm. The company employs approximately 17,000 staff members. Its products include Epogen, Aranesp, Enbrel, Kineret,... |
USA | 14,268.0 | 3,366.0 | 2,950.0 | 20,100 |
| 2 | Genentech Genentech Genentech Inc., or Genetic Engineering Technology, Inc., is a biotechnology corporation, founded in 1976 by venture capitalist Robert A. Swanson and biochemist Dr. Herbert Boyer. Trailing the founding of Cetus by five years, it was an important step in the evolution of the biotechnology industry... |
USA | 11,724.0 | 2,995.0 | 2,740.0 | 10,001+ |
| 3 | Genzyme Genzyme Genzyme Corporation is a fully owned subsidiary of Sanofi-Aventis. Before its acquisition, Genzyme was an American biotechnology company based in Cambridge, Massachusetts. In 2010, Genzyme was the world’s third-largest biotechnology company, employing more than 11,000 people around the world... |
USA | 3,187.0 | 650.0 | (16.8) | 9,000+ |
| 4 | UCB UCB (company) UCB is a multinational biopharmaceutical manufacturing company headquartered in Brussels, Belgium.- History :UCB was founded on 18 January 1928 by Emmanuel Janssen, a Belgian businessman... |
Belgium | 3,169.6 | 772.6 | 461.1 | 8,477 |
| 5 | Gilead Sciences Gilead Sciences Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes therapeutics. For many years since the company was founded, the company concentrated primarily on antiviral drugs to treat patients infected with HIV, hepatitis B or influenza. In 2006, Gilead acquired two... |
USA | 3,026.1 | 383.9 | (1,190.0) | 7,575 |
| 6 | Serono Serono Serono is a biotechnology company headquartered in Geneva, Switzerland. The company was founded as the Serono Pharmacolodgical Institute by Cesare Serono in 1906 in Italy. A key step in its development was the discovery of a method of extracting urinary gonadotropins by Dr Piero Donini allowing... |
Switzerland | 2,804.9 | 560.5 | 735.4 | 4,775 |
| 7 | Biogen Idec Biogen Idec Biogen Idec, Inc. is a biotechnology company specializing in drugs for neurological disorders, autoimmune disorders and cancer. The company was formed in 2003 by the merger of Cambridge, Massachusetts-based Biogen Inc. and San Diego, California-based IDEC Pharmaceuticals... |
USA | 2,683.0 | 718.4 | 217.5 | 3,750 |
| 8 | CSL CSL Limited CSL Limited is a global specialty biopharmaceutical company that researches, develops, manufactures and markets products to treat and prevent serious human medical conditions... |
Australia | 2,148.3 | 119.1 | 86.8 | 2,895 |
| 9 | Cephalon Cephalon Cephalon, Inc. is a U.S. biopharmaceutical company co-founded in 1987 by Dr. Frank Baldino, Jr., a pharmacologist and former scientist with the DuPont Company, who served as the company's chairman and chief executive officer until his death in December 2010... |
USA | 1,764.1 | 403.4 | 144.8 | 2,515 |
| 10 | MedImmune MedImmune MedImmune, LLC, headquartered in Gaithersburg, Maryland, became a wholly owned subsidiary of AstraZeneca in 2007. Since being acquired, MedImmune has remained a Maryland-based biotechnology development enterprise... |
USA | 1,276.8 | 448.9 | 48.7 | 2,359 |
| 11 | Celgene Celgene Celgene Corporation is a manufacturer of drug therapies for cancer and inflammatory disorders. It is incorporated in Delaware and headquartered in Summit, New Jersey... |
USA | 898.9 | 258.6 | 69.0 | 1,864 |
| 12 | Abraxis BioScience Abraxis BioScience Abraxis BioScience is a global biopharmaceutical company dedicated to meeting the needs of critically ill patients, with over 2000 employees worldwide.-Description:... |
USA | 765.5 | 96.9 | (46.9) | 1,734 |
| 13 | Actelion Actelion Actelion was founded in December 1997 and is headquartered in Allschwil near Basel . Its CEO and co-founder is cardiologist Jean-Paul Clozel. Actelion scientists were among the first to work in the field of endothelian receptor antagonists... |
Switzerland | 754.6 | 169.0 | 192.4 | 1,550 |
| 14 | ImClone Systems ImClone Systems ImClone Systems Incorporated is a biopharmaceutical company dedicated to developing biologic medicines in the area of oncology. It was founded in 1984 and is headquartered in New York City. On October 6, 2008, it accepted a $6.5 billion acquisition offer from Eli Lilly and Company, and became a... |
USA | 677.8 | 112.1 | 370.7 | 1,287 |
| 15 | Amylin Pharmaceuticals Amylin Pharmaceuticals Amylin Pharmaceuticals is a biopharmaceutical company based in San Diego, CA, that was founded in 1987. The company is engaged in the discovery, development and commercialization of drug candidates for the treatment of diabetes, obesity and other diseases. Currently, Amylin produces two drugs,... |
USA | 510.9 | 222.1 | (218.9) | 1,100 |
| 16 | Millennium Pharmaceuticals Millennium Pharmaceuticals Millennium Pharmaceuticals, Inc., The Takeda Oncology Company is a biopharmaceutical company based in Cambridge, Massachusetts. The Company markets Velcade for injection, a cancer product, and has a growing clinical development pipeline of product candidates... |
USA | 486.8 | 318.2 | (44.0) | 1,073 |
| 17 | PDL BioPharma | USA | 414.8 | 260.7 | (130.0) | 993 |
| 18 | OSI Pharmaceuticals OSI Pharmaceuticals OSI Pharmaceuticals, Inc. is an American pharmaceutical company based in Long Island, New York with facilities in Colorado, New Jersey and the United Kingdom. OSI specializes in the discovery and development of molecular targeted therapies, and was listed in the NASDAQ Biotechnology Index... |
USA | 375.7 | 176.7 | (582.2) | 962 |
| 19 | MGI Pharma | USA | 342.8 | 100.1 | (40.2) | 947 |
| 20 | Pharmion | USA | 238.6 | 70.1 | (91.0) | 793 |
| 21 | Nektar Therapeutics | USA | 217.7 | 149.4 | (154.8) | 770 |
| 22 | Vertex Pharmaceuticals Vertex Pharmaceuticals Vertex Pharmaceuticals is a biotechnology company with activities spanning the length of the pharmaceutical product pipeline, from target identification through to clinical trials and marketing. Most of its activity has been in collaboration with much larger pharmaceutical firms, though some of its... |
USA | 216.4 | 371.7 | (206.9) | 760 |
| 23 | Biocon Biocon Biocon Limited is a global biopharmaceutical company with products and research services ranging from pre-clinical to clinical development through to commercialization. Within biopharmaceuticals, the Company manufactures generic active pharmaceutical ingredients like Statins and... |
India | 200.3 | 30.5 | 43.5 | 1,838 |
| 24 | Cubist Pharmaceuticals Cubist Pharmaceuticals Cubist Pharmaceuticals is a biopharmaceutical company with activities spanning from research and development to commercialization of pharmaceutical products. Its main products address unmet medical needs in acute care, specifically pathogens like MRSA... |
USA | 194.7 | 57.4 | (0.4) | 746 |
| 25 | Enzon Pharmaceuticals | USA | 185.7 | 43.5 | 21.3 | 722 |
| 26 | QLT | Canada | 175.1 | 56.4 | (101.6) | 653 |
| 27 | ViroPharma ViroPharma ViroPharma Incorporated, a pharmaceutical company, develops and sells drugs that address serious diseases treated by physician specialists and in hospital settings... |
USA | 167.2 | 19.2 | 66.7 | 651 |
| 28 | Alkermes | USA | 166.6 | 89.1 | 3.8 | 617 |
| 29 | Crucell Crucell Crucell is a biotechnology company specializing in vaccines and antibodies. The firm, a subsidiary of Johnson & Johnson, is headquartered in Leiden, Netherlands... |
Netherlands | 165.3 | 84.9 | (110.0) | 611 |
| 30 | United Therapeutics | USA | 159.6 | 57.6 | 74.0 | 585 |
| 31 | LifeCell LifeCell LifeCell is a biotechnology company that develops and sells tissue grafts and blood cell preservation products. In recent years, LifeCell's sales have grown at an average of 41% per year and profits up to 72% annually, due in part to rising sales of their human tissue product AlloDerm... |
USA | 141.7 | 16.5 | 20.5 | 573 |
| 32 | Ligand Pharmaceuticals | USA | 141.0 | 41.9 | (31.7) | 540 |
| 33 | Myriad Genetics Myriad Genetics Myriad Genetics, Inc. is a molecular diagnostic company based in Salt Lake City, Utah. Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease... |
USA | 114.3 | 83.8 | (38.2) | 511 |
| 34 | Exelixis Exelixis Exelixis is a genomics-based drug discovery company located in South San Francisco, Ca. It works on the development of anti-cancer therapies. Exelixis has several compounds in various stages of FDA approval including :... |
USA | 98.7 | 185.5 | (101.5) | 500 |
| 35 | Cangene Cangene Cangene Corporation is a pharmaceutical company based in Winnipeg. Manitoba, Canada. It was founded in 1984 and specialized in hyperimmunes, contract manufacturing, biopharmaceuticals and biodefense... |
Canada | 96.8 | 22.1 | 11.6 | 498 |
| 36 | InterMune | USA | 90.8 | 103.8 | (107.2) | 492 |
| 37 | Nabi Biopharmaceuticals | USA | 89.9 | 37.6 | (58.7) | 487 |
| 38 | BioMarin Pharmaceutical BioMarin Pharmaceutical BioMarin Pharmaceutical Inc. is a biotechnology firm based in Novato, California. It has offices and facilities in the US, South America, Asia and Europe. BioMarin's core business and research is in enzyme replacement therapies... |
USA | 84.2 | 66.7 | (28.5) | 417 |
| 39 | Lexicon Pharmaceuticals Lexicon Pharmaceuticals Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company engaged in discovering and developing breakthrough treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated... |
USA | 72.8 | 106.7 | (54.3) | 410 |
| 40 | Progenics Pharmaceuticals | USA | 69.9 | 61.7 | (21.6) | 410 |
| 41 | Innogenetics Innogenetics Innogenetics NV is an international in vitro diagnostics company, with headquarters in Ghent, Belgium. The company develops and markets diagnostic assays in the fields of infectious diseases, oncology, neurodegeneration, transplantation and genetic testing, with a special focus on molecular... |
Belgium | 67.5 | 32.1 | (31.5) | 371 |
| 42 | Idenix Pharmaceuticals | USA | 67.4 | 96.1 | (75.1) | 359 |
| 43 | MorphoSys MorphoSys MorphoSys AG is a German biotechnology company. It is involved in the development and research of antibodies. TecDAX has listed MorphoSys since 2004.-Technology:MorphoSys generates human antibodies that contain 100% human proteins... |
Germany | 66.6 | 21.9 | 7.6 | 336 |
| 44 | Omrix Biopharmaceuticals | USA | 63.8 | 3.4 | 23.1 | 335 |
| 45 | Regeneron Pharmaceuticals | USA | 63.4 | 137.1 | (102.3) | 323 |
| 46 | Acambis | UK | 57.0 | 68.2 | (30.4) | 285 |
| 47 | Tanox Tanox Tanox was a biopharmaceutical company based in Houston, Texas. The company was founded by two biomedical research scientists, Nancy T. Chang and Tse Wen Chang in March 1986. Nancy was the President and CEO of the company in its 21 year history, while Tse Wen was responsible for creating most of the... |
USA | 56.1 | 53.4 | (2.6) | 285 |
| 48 | ViaCell | USA | 54.4 | 14.0 | (21.0) | 282 |
| 49 | Indevus Pharmaceuticals | USA | 50.5 | 43.2 | -50.6 | 279 |
| 50 | Medarex Medarex Medarex is an American biotechnology company owned by Bristol Myers Squibb and based in Princeton, New Jersey. The company has manufacturing facilities in Bloomsbury and Annandale, New Jersey, and research facilities in Milpitas and Sunnyvale, California. Medarex specializes in therapeutic... |
USA | 48.6 | 194.5 | (181.7) | 277 |
| 51 | NPS Pharmaceuticals | USA | 48.5 | 68.4 | (112.7) | 276 |
| 52 | Monogram Biosciences Monogram Biosciences Monogram Biosciences Inc. , a wholly owned subsidiary of LabCorp, is an international biotechnology laboratory located in South San Francisco, California, USA... |
USA | 48.0 | 19.0 | (38.7) | 274 |
| 53 | Oscient Pharmaceuticals | USA | 46.2 | 12.4 | (78.5) | 267 |
| 54 | Array BioPharma | USA | 45.0 | 33.4 | (39.6) | 263 |
| 55 | AEterna Zentaris Aeterna Zentaris Æterna Zentaris Inc. is a Quebec, Canada-based biopharmaceutical company focused in oncology and endocrine therapy. It has over 100 employees in Canada, USA and Germany. The company is based in Canada, the development and research site ist based in Germany... |
Canada | 41.4 | 28.7 | 33.4 | 260 |
| 56 | IsoTis | Switzerland | 40.7 | 7.7 | (18.5) | 255 |
| 57 | Enzo Biochem | USA | 39.8 | 7.9 | (15.7) | 255 |
| 58 | CuraGen | USA | 39.6 | 58.5 | (59.8) | 254 |
| 59 | Neurocrine Biosciences Neurocrine Biosciences Neurocrine Biosciences is a biopharmaceutical company founded in 1992 and located in San Diego, California. The company tooks its name from the original focus on therapies for neurological and endocrine diseases and disorders.... |
USA | 39.2 | 97.7 | (107.2) | 254 |
| 60 | MediGene MediGene MediGene AG is a German biotechnology company. It is involved in the development of anti pancreatic cancer drugs. The company has two marketed products: Eligard for prostate cancer and Veregen for genital warts... |
Germany | 38.4 | 26.7 | (8.7) | 248 |
| 61 | Life Therapeutics | Australia | 37.6 | 0.1 | (31.2) | 245 |
| 62 | Inspire Pharmaceuticals | USA | 37.1 | 42.5 | (42.1) | 238 |
| 63 | CV Therapeutics | USA | 36.8 | 135.3 | (274.3) | 233 |
| 64 | Cerus | USA | 35.6 | 29.5 | (4.8) | 208 |
| 65 | SciClone Pharmaceuticals | USA | 32.7 | 14.1 | 0.7 | 197 |
| 66 | ImmunoGen | USA | 32.1 | 40.9 | (17.8) | 197 |
| 67 | Protherics | UK | 30.9 | 11.8 | (16.5) | 196 |
| 68 | Arena Pharmaceuticals Arena Pharmaceuticals Arena Pharmaceuticals, Inc. is a biopharmaceutical company located in San Diego, California. The company is developing oral medications that target G-protein-coupled receptors. Currently none of the drugs is approved by the U.S... |
USA | 30.6 | 103.4 | (88.3) | 195 |
| 69 | Vernalis | UK | 30.1 | 71.7 | (78.2) | 192 |
| 70 | Bavarian Nordic | Denmark | 29.5 | 19.9 | (27.1) | 191 |
| 71 | Xoma | USA | 29.5 | 52.1 | (51.8) | 189 |
| 72 | GPC Biotech GPC Biotech GPC Biotech is a German biopharmaceutical company. The company's mission statement reads "... to discover, develop and commercialize new anticancer drugs."... |
Germany | 28.5 | 81.3 | (80.4) | 180 |
| 73 | Micromet | USA | 27.6 | 28.3 | 0.0 | 171 |
| 74 | Targacept Targacept Targacept is a pharmaceutical company based in Winston-Salem, North Carolina that specializes in developing drugs which target the nicotinic acetylcholine receptors.... |
USA | 27.5 | 21.8 | (1.2) | 170 |
| 75 | Carrington Laboratories | USA | 27.4 | 5.8 | (7.6) | 166 |
| 76 | Acorda Therapeutics Acorda Therapeutics Acorda Therapeutics is a biotechnology company based in Hawthorne, New York. Acorda Therapeutics develops drugs to improve therapies that improve neurological function in people with multiple sclerosis, spinal cord injury and other disorders of the central nervous system... |
USA | 27.4 | 12.1 | (60.0) | 158 |
| 77 | Anika Therapeutics | USA | 26.8 | 3.6 | 4.6 | 156 |
| 78 | Human Genome Sciences Human Genome Sciences Human Genome Sciences is a biopharmaceutical corporation founded in 1992. It uses the human DNA sequence to develop protein and antibody drugs. As of 2008, it has drugs under development to treat such diseases as hepatitis C, systemic lupus erythmatosis, anthrax disease, cancer, rheumatoid... |
USA | 25.8 | 209.2 | (251.2) | 151 |
| 79 | Dusa Pharmaceuticals DUSA Pharmaceuticals DUSA Pharmaceuticals, Inc. is pharmaceutical company based in Wilmington, Massachusetts that specializes in dermatology products. The major focus of the company includes medications used in the treatment of actinic keratoses and acne.... |
USA | 25.6 | 6.2 | (31.3) | 150 |
| 80 | ZymoGenetics ZymoGenetics ZymoGenetics is a biotechnology/pharmaceutical company based in Seattle, Washington, involved in the development of therapeutic proteins.The company was founded in 1981 by Professors Earl W. Davie and Benjamin D. Hall of the University of Washington and 1993 Nobel Laureate in Chemistry Michael... |
USA | 25.4 | 128.5 | (130.0) | 150 |
| 81 | Maxygen Maxygen Maxygen Inc. is a biopharmaceutical company focused on developing improved versions of protein drugs using DNA shuffling and other protein modification technologies... |
USA | 25.0 | 49.1 | (16.5) | 147 |
| 82 | Isis Pharmaceuticals | USA | 24.5 | 80.6 | (45.9) | 133 |
| 83 | Genmab Genmab Genmab A/S is a Danish biotechnology company, founded in February 1999 and based in Copenhagen. Internationally, it operates through the subsidiaries Genmab BV in Utrecht, The Netherlands, and Genmab, Inc in Princeton, New Jersey, USA. The Company is publicly traded on the NASDAQ OMX Copenhagen A/S... |
Denmark | 23.9 | 90.6 | (77.4) | 128 |
| 84 | BioSciMed | USA | 23.9 | 11.6 | (1.0) | 126 |
| 85 | Bioniche Life Sciences | Canada | 24.1 | 11.9 | (1.0) | 127 |
| 86 | Vitrolife | Sweden | 23.2 | 3.3 | 2.1 | 124 |
| 87 | Coley Pharmaceutical Group | USA | 20.2 | 40.9 | (29.4) | 122 |
| 88 | Palatin Technologies | USA | 19.7 | 41.0 | (29.0) | 116 |
| 89 | Encysive Pharmaceuticals Pfizer Pfizer, Inc. is an American multinational pharmaceutical corporation. The company is based in New York City, New York with its research headquarters in Groton, Connecticut, United States... |
USA | 19.0 | 64.4 | (109.3) | 109 |
| 90 | GenVec GenVec GenVec, Inc. is a biopharmaceutical company developing pharmaceuticals and vaccines based on novel biotechnology such as targeted delivery systems. The company has a number of drugs currently in various phases of clinical trials. Its lead product candidate is TNFerade, being developed for the... |
USA | 18.9 | 29.6 | (19.3) | 95 |
| 91 | Medivir Group | Sweden | 18.8 | 39.7 | (29.7) | 88 |
| 92 | Peptech Peptech Peptech Limited used to be an Australian biotechnology company listed on the Australian Stock Exchange. Peptech described its operations as "...an ASX-listed Australian biotechnology company dedicated to developing and providing antibody and peptide-based human therapeutic products for the... |
Australia | 18.7 | 4.6 | 3.8 | 85 |
| 93 | Ambrilia Biopharma | Canada | 17.4 | 8.3 | (2.1) | 85 |
| 94 | Cytogen | USA | 17.3 | 7.3 | (15.1) | 85 |
| 95 | Replidyne | USA | 16.0 | 38.3 | (34.6) | 79 |
| 96 | Sinovac Biotech Sinovac Biotech Sinovac Biotech Ltd. is a biopharmaceutical company that focuses on the research, development, manufacture and commercialization of vaccines that protect against human infectious diseases. The company is based in Beijing, China.... |
China | 15.4 | 0.3 | (0.7) | 67 |
| 97 | Trimeris | USA | 15.2 | 18.3 | 7.4 | 64 |
| 98 | Avanir Pharmaceuticals | USA | 15.2 | 29.2 | (62.6) | 64 |
| 99 | Adolor | USA | 15.1 | 56.7 | (69.7) | 51 |