Leriche's syndrome
Encyclopedia
In medicine
, aortoiliac occlusive disease, also known as Leriche's syndrome and Leriche syndrome, is atherosclerotic occlusive disease involving the abdominal aorta
and/or both of the iliac arteries.
s consisting of:
This combination is known as Leriche syndrome.http://onlinesurgicaldictionary.com/arteries/obliterative-atheromatous-disease/aortoiliac-disease However, any number of symptoms may present, depending on the distribution and severity of the disease. Variable, chronic ischemia involving the lower limbs is a common presentation.http://www.jvascbr.com.br/02-01-01/02-01-01-47/02-01-01-47.htm
Investigations:
Angiography (aortography)
Doppler
in 1814, but the condition with its triad of symptoms was ascribed to René Leriche
. Leriche, a French
surgeon, linked the pathophysiology
with the anatomy
of the condition. John Hunter's dissections of atherosclerotic aortic bifurcations from the late 18th century are preserved at the Hunterian Museum, but Leriche was first to publish on the subject based on a patient he treated with the condition at the age of 30. Following treatment the 30 year old was able to walk without pain and maintain an erection.
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....
, aortoiliac occlusive disease, also known as Leriche's syndrome and Leriche syndrome, is atherosclerotic occlusive disease involving the abdominal aorta
Abdominal aorta
The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of the descending aorta .-Path:...
and/or both of the iliac arteries.
Symptoms
Classically, it is described in male patients as a triad of symptomSymptom
A symptom is a departure from normal function or feeling which is noticed by a patient, indicating the presence of disease or abnormality...
s consisting of:
- claudicationClaudicationClaudication, literally 'limping' , is a medical term usually referring to impairment in walking, or pain, discomfort or tiredness in the legs that occurs during walking and is relieved by rest. The perceived level of pain from claudication can be mild to extremely severe. Claudication is most...
of the buttocks and thighs - atrophy of the musculature of the legs
- impotence
This combination is known as Leriche syndrome.http://onlinesurgicaldictionary.com/arteries/obliterative-atheromatous-disease/aortoiliac-disease However, any number of symptoms may present, depending on the distribution and severity of the disease. Variable, chronic ischemia involving the lower limbs is a common presentation.http://www.jvascbr.com.br/02-01-01/02-01-01-47/02-01-01-47.htm
Investigations:
Angiography (aortography)
Doppler
Treatment
- AortoAortaThe aorta is the largest artery in the body, originating from the left ventricle of the heart and extending down to the abdomen, where it branches off into two smaller arteries...
iliacIliac arteryIn human anatomy, iliac artery refers to several anatomical structures located in the pelvis:*Common iliac artery - forms at terminus of the aorta...
bypass graft - AxilloAxillary arteryIn human anatomy, the axillary artery is a large blood vessel that conveys oxygenated blood to the lateral aspect of the thorax, the axilla and the upper limb...
femoralFemoral arteryThe femoral artery is a general term comprising a few large arteries in the thigh. They begin at the inguinal ligament and end just above the knee at adductor canal or Hunter's canal traversing the extent of the femur bone....
and femoral-femoral bypass (sometimes abbreviated "ax-fem fem-fem")
Discovery
The condition was first described by Robert GrahamRobert Graham
Robert Graham may refer to:*Sir Robert Graham , one of the assassins of James I of Scotland*Robert Graham of Gartmore , Scottish politician and poet...
in 1814, but the condition with its triad of symptoms was ascribed to René Leriche
René Leriche
René Leriche was a famous French surgeon.-Eponymous terms:René Leriche gave his name to two syndromes:...
. Leriche, a French
French people
The French are a nation that share a common French culture and speak the French language as a mother tongue. Historically, the French population are descended from peoples of Celtic, Latin and Germanic origin, and are today a mixture of several ethnic groups...
surgeon, linked the pathophysiology
Pathophysiology
Pathophysiology is the study of the changes of normal mechanical, physical, and biochemical functions, either caused by a disease, or resulting from an abnormal syndrome...
with the anatomy
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...
of the condition. John Hunter's dissections of atherosclerotic aortic bifurcations from the late 18th century are preserved at the Hunterian Museum, but Leriche was first to publish on the subject based on a patient he treated with the condition at the age of 30. Following treatment the 30 year old was able to walk without pain and maintain an erection.
External links
- Aortoiliac occlusive disease vascularweb.org
- Leriche's syndrome - whonamedit.com
- Coronal CT of Leriche' syndrome - learningradiology.com