Leonard I. Zon
Encyclopedia
Leonard I. Zon, M.D., is the Grousbeck Professor of Pediatric Medicine at Harvard Medical School
Harvard Medical School
Harvard Medical School is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts....

, Investigator at Howard Hughes Medical Institute
Howard Hughes Medical Institute
Howard Hughes Medical Institute is a United States non-profit medical research organization based in Chevy Chase, Maryland. It was founded by the American businessman Howard Hughes in 1953. It is one of the largest private funding organizations for biological and medical research in the United...

, and Director of the Stem Cell
Stem cell
This article is about the cell type. For the medical therapy, see Stem Cell TreatmentsStem cells are biological cells found in all multicellular organisms, that can divide and differentiate into diverse specialized cell types and can self-renew to produce more stem cells...

 Program, Children’s Hospital Boston.

He received a B.S. degree in chemistry and natural sciences from Muhlenberg College
Muhlenberg College
Muhlenberg College is a private liberal arts college located in Allentown, Pennsylvania, United States. Founded in 1848, Muhlenberg is affiliated with the Evangelical Lutheran Church in America and is named for Henry Melchior Muhlenberg, the patriarch of the Lutheran Church in America.- History...

 and an M.D. degree from Jefferson Medical College. He subsequently did an internal medicine residency at New England Deaconess Hospital and a fellowship in medical oncology
Oncology
Oncology is a branch of medicine that deals with cancer...

 at Dana-Farber Cancer Institute
Dana-Farber Cancer Institute
Dana–Farber Cancer Institute is part of a Comprehensive Cancer Center designated by the National Cancer Institute. It is a major affiliate of Harvard Medical School and is located in the Longwood Medical Area in Boston, Massachusetts.-Overview:...

. His postdoctoral research was in the laboratory of Stuart Orkin.

Research

Dr. Leonard Zon is internationally recognized for his pioneering work in the fields of stem cell biology and cancer genetics. He is founder and former president of the International Society for Stem Cell Research and chair of the Executive Committee of the newly formed Harvard Stem Cell Institute (HSCI). He recently completed a term as President of the American Society for Clinical Investigation
American Society for Clinical Investigation
The American Society for Clinical Investigation, or ASCI, established in 1908, is one of the nation's oldest and most respected medical honor societies.-Organization and Purpose:...

. In 2005, Dr. Zon was elected to the Institute of Medicine
Institute of Medicine
The Institute of Medicine is a not-for-profit, non-governmental American organization founded in 1970, under the congressional charter of the National Academy of Sciences...

 of the National Academies. In 2008, Dr. Zon was elected to the American Academy of Arts & Sciences.

Dr. Zon's laboratory uses the zebrafish as a model system for understanding vertebrate blood development. Zebrafish blood formation is similar to that of humans, and several mutants have disorders resembling human disease. It is possible to evaluate in the zebrafish genetic pathways important for vertebrate hematopoiesis. Dr. Zon also uses the zebrafish to study cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

.
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