Lapdap
Encyclopedia
Chlorproguanil/dapsone was a fixed dose antimalarial combination containing chlorproguanil
and dapsone
, which act synergystically against malaria
. The drug was withdrawn in 2008 following increasing evidence of toxicity in the form of haemolysis occurring in patients with G6PD deficiency.
Chlorproguanil
Chlorproguanil is an antimalarial drug.-See also:* Proguanil* Chlorproguanil hydrochloride-dapsone-artesunate...
and dapsone
Dapsone
Dapsone is a medication most commonly used in combination with rifampicin and clofazimine as multidrug therapy for the treatment of Mycobacterium leprae infections . It is also second-line treatment for prophylaxis against Pneumocystis pneumonia caused by Pneumocystis jiroveci Dapsone...
, which act synergystically against malaria
Malaria
Malaria is a mosquito-borne infectious disease of humans and other animals caused by eukaryotic protists of the genus Plasmodium. The disease results from the multiplication of Plasmodium parasites within red blood cells, causing symptoms that typically include fever and headache, in severe cases...
. The drug was withdrawn in 2008 following increasing evidence of toxicity in the form of haemolysis occurring in patients with G6PD deficiency.