Karl Leopold of Mecklenburg-Schwerin
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Karl Leopold of Mecklenburg-Schwerin (26 September 1678 Grabow
Grabow
Grabow is a town in the Ludwigslust-Parchim district, in Mecklenburg-Western Pomerania, Germany. It is situated on the river Elde, 7 km southeast of Ludwigslust, and 34 km northwest of Wittenberge.-History:...

– 28 November 1747 Domitz
Dömitz
Dömitz is a municipality in the Ludwigslust-Parchim district, in Mecklenburg-Western Pomerania, Germany. It is situated on the right bank of the Elbe, 25 km southwest of Ludwigslust, and 37 km northwest of Wittenberge....

) was the Duke of Mecklenburg-Schwerin
Mecklenburg-Schwerin
Mecklenburg-Schwerin was a duchy in northern Germany created in 1348, when Albert II of Mecklenburg and his younger brother John were raised to Dukes of Mecklenburg by King Charles IV...

 from 1713-1747.

He was the second son of Friedrich I von Mecklenburg-Schwerin (1638-1688)
Frederick, Duke of Mecklenburg-Grabow
Frederick I of Mecklenburg-Grabow, Duke of Mecklenburg [-Grabow] - Life :He was the son of Adolf Frederick I, Duke of Mecklenburg-Schwerin and his second wife Marie Katharina , daughter of Julius Ernst, Duke of Braunschweig-Dannenberg .Through his late birth, he was excluded from active government...

 and his wife, née Christine von Hessen-Homburg (1653–1722), and succeeded his brother Friedrich Wilhelm von Mecklenburg-Schwerin as duke in 1713.

Karl Leopold married three times. His first wife was Sophia Hedwig of Nassau-Dietz (1690–1734), daughter of Heinrich Kasimir II von Nassau-Dietz (1657–1696) and his wife, née Henriëtte Amalia von Anhalt-Dessau
Henriëtte Amalia van Anhalt-Dessau
Henriëtte Amalia Maria van Anhalt-Dessau was the daughter of John George II, Prince of Anhalt-Dessau and Henriëtte Catharina of Nassau and the granddaughter of Frederick Henry, Prince of Orange....

 (1666–1726). They married on 27 May 1709 in Leeuwarden and divorced in 1710. There were no children of this marriage.

His second wife was Christine von Lepel (1692–1728), daughter of Nicolaus Friedrich von Lepel and his wife née Leveka von Plessen. They married 7 June 1710 at Doberau, and divorced on 2 October 1711. There were no children of this marriage.

His third wife was Grand Duchess Jekaterina Ivanovna of Russia (1692–1733), daughter of Tsar Ivan V of Russia
Ivan V of Russia
Ivan V Alekseyevich Romanov was a joint Tsar of Russia who co-reigned between 1682 and 1696. He was the youngest son of Alexis I of Russia and Maria Miloslavskaya. His reign was only formal, since he had serious physical and mental disabilities...

 (1666–1696) and his wife, née Praskovaya Feodorovna Saltykova
Praskovia Saltykova
Praskovia Fyodorovna Saltykova was the tsaritsa of Russia as the only wife of Ivan V of Russia. She was the mother of Empress Anna of Russia...

. They married on 19 April 1716 at Danzig. There was one daughter born of this marriage, Elisabeth Katharina Christina of Mecklenburg-Schwerin, known as Anna Leopoldovna. She married Anton Ulrich, Duke of Brunswick-Bevern-Luneburg
Duke Anthony Ulrich of Brunswick
Anthony Ulrich , Duke of Brunswick-Lüneburg, was generalissimus of the Army of Russia, and husband to Anna Leopoldovna, who was regent of Russia for one year.- Biography :...

, and had 5 children. She served as Regent of Russia for her son Ivan VI
Ivan VI of Russia
Ivan VI Antonovich of Russia , was proclaimed Emperor of Russia in 1740, as an infant, although he never actually reigned. Within less than a year, he was overthrown by the Empress Elizabeth of Russia, Peter the Great's daughter...

from 1740-1741.
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