KCNA7
Encyclopedia
Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein
that in humans is encoded by the KCNA7 gene
. The protein
encoded by this gene is a voltage-gated potassium channel
subunit. It may contribute to the cardiac transient outward potassium current
(Ito1), the main contributing current to the repolarizing
phase 1 of the cardiac action potential.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the KCNA7 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. The protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
encoded by this gene is a voltage-gated potassium channel
Voltage-gated potassium channel
Voltage-gated potassium channels are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential. During action potentials, they play a crucial role in returning the depolarized cell to a resting state....
subunit. It may contribute to the cardiac transient outward potassium current
Cardiac transient outward potassium current
The cardiac transient outward potassium current is the main contributing current to the repolarizing phase 1 of the cardiac action potential, and results from movement of potassium ions from the intracellular to the extracellular space...
(Ito1), the main contributing current to the repolarizing
Repolarization
In neuroscience, repolarization refers to the change in membrane potential that returns the membrane potential to a negative value after the depolarization phase of an action potential has just previously changed the membrane potential to a positive value. Repolarization results from the movement...
phase 1 of the cardiac action potential.