Journal of Orthomolecular Medicine
Encyclopedia
The Journal of Orthomolecular Medicine was established in 1967 by Abram Hoffer
Abram Hoffer
Abram Hoffer was a Canadian biochemist, physician and psychiatrist. Hoffer developed a theory that nutrition and vitamins may be effective treatments for schizophrenia...

. It publishes studies in nutrition
Nutrition
Nutrition is the provision, to cells and organisms, of the materials necessary to support life. Many common health problems can be prevented or alleviated with a healthy diet....

al and orthomolecular medicine
Orthomolecular medicine
Orthomolecular medicine is a form of complementary and alternative medicine that seeks to maintain health and prevent or treat diseases by optimizing nutritional intake and/or prescribing supplements...

. There is controversy surrounding the journal, as the validity of the field of orthomolecular medicine is not widely accepted by mainstream medicine.

History

In 1967, Hoffer found it increasingly difficult to publish reports on his studies of megavitamin therapies
Megavitamin therapy
Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance in the attempt to prevent or treat diseases...

 and claimed that his studies were rejected in a conspiracy of mainstream medicine, prompted by what he alleged to be extended conflicts of interest on the part of the American Psychiatric Association
American Psychiatric Association
The American Psychiatric Association is the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the most influential worldwide. Its some 38,000 members are mainly American but some are international...

. The Journal of Schizophrenia followed the formation of the Canadian Schizophrenia Foundation and the American Schizophrenia Association. Hoffer and Humphry Osmond
Humphry Osmond
Humphry Fortescue Osmond was a British psychiatrist known for inventing the word psychedelic and for using psychedelic drugs in medical research...

, who developed the hypothesis
Hypothesis
A hypothesis is a proposed explanation for a phenomenon. The term derives from the Greek, ὑποτιθέναι – hypotithenai meaning "to put under" or "to suppose". For a hypothesis to be put forward as a scientific hypothesis, the scientific method requires that one can test it...

 that schizophrenia
Schizophrenia
Schizophrenia is a mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests itself as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social...

 is caused by the endogenous production of an epinephrine
Epinephrine
Epinephrine is a hormone and a neurotransmitter. It increases heart rate, constricts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system. In chemical terms, adrenaline is one of a group of monoamines called the catecholamines...

 (adrenaline) based hallucinogen
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...

, were called before the Committee of Ethics of the American Psychiatric Association to explain why they were publicizing a treatment, called xenobiotic psychiatry by Bernard Rimland
Bernard Rimland
Bernard Rimland, PhD was an American research psychologist, writer, lecturer, and advocate for autistic children, ADHD, learning disabilities, and mental retardation.Based in San Diego, California since 1940, Dr...

, which was considered outside of standard psychiatric practice. Hoffer claims that one of the assistant editors of the American Journal of Psychiatry
American Journal of Psychiatry
The American Journal of Psychiatry is a monthly peer-reviewed medical journal covering all aspects of psychiatry and the official journal of the American Psychiatric Association. The first volume was issued in 1844, at which time it was known as the American Journal of Insanity...

announced that he would never allow any article from Hoffer's group to appear in his journal.

Several name changes occurred: to Schizophrenia; then to Orthomolecular Psychiatry, ostensibly to reflect the increased application of this type of therapy to other mental illnesses; then to Journal of Orthomolecular Medicine.

Controversial status

The Journal of Orthomolecular Medicine is not indexed by MEDLINE
MEDLINE
MEDLINE is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care...

, a database of biomedical literature. Journals are selected for MEDLINE by the National Library of Medicine
United States National Library of Medicine
The United States National Library of Medicine , operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is a division of the National Institutes of Health...

, according to criteria including scope and coverage, quality of content, quality of editorial work, intended audience, quality of the layout, printing, graphics, and illustrations. Exclusion from MEDLINE for the last 30 years has been interpreted by its supporters as confirmation of an alleged bias against orthomolecular medicine. The editors of the Journal of Orthomolecular Medicine compare it favorably with and as similar to Medical Hypotheses
Medical Hypotheses
Medical Hypotheses is a medical journal published by Elsevier. It was originally intended as a forum for unconventional ideas without the traditional filter of scientific peer review, "so long as are coherent and clearly expressed" in order to "foster the diversity and debate upon which the...

, which is indexed. The journal is classified as a "Non-recommended Periodical" by the alternative medicine watchdog
Watchdog journalism
Watchdog journalism aims to hold accountable public personalities and institutions, whose functions impact social and political life. The term "lapdog journalism", for journalism biased in favour of personalities and institutions, is sometimes used as a conceptual opposite to watchdog...

 website, Quackwatch.org
Quackwatch
Quackwatch is an American non-profit organization founded by Stephen Barrett with the stated aim being to "combat health-related frauds, myths, fads, fallacies, and misconduct" and with a primary focus on providing "quackery-related information that is difficult or impossible to get elsewhere."...

.
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