James Frederic Danielli was an English biologist.

He was famous for research on the structure and the permeability of cell membranes, developing a physical-chemical model in collaboration with the physiologist Hugh Davson

Hugh Davson

Hugh Davson was a 20th century English physiologist who worked on membrane transport and ocular fluids.He attended University College School. He later studied at University College London and took a variety of research posts at institutes such as UCL, and Canada's Dalhousie University...

. This became known as the Davson-Danielli

Davson-Danielli model

In 1935, Hugh Davson and James Danielli proposed a model of the cell membrane in which the phospholipid bilayer lay between two layers of globular protein...

or "protein sandwich" model. He also carried out studies on the chemistry of enzymes and proteins and tried to construct an artificial "cell".