Interleukin-11 receptor
Encyclopedia
The interleukin 11 receptor is a type I cytokine receptor
, binding interleukin 11
. It is a heterodimer composed of an interleukin 11 receptor alpha subunit
and an incompletely characterized beta subunit.
Type I cytokine receptor
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name hemopoietin receptors, and share a common amino acid motif in the extracellular portion...
, binding interleukin 11
Interleukin 11
Interleukin 11 is a protein that in humans is encoded by the IL11 gene.IL-11 is a multifunctional cytokine first isolated in 1990 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation...
. It is a heterodimer composed of an interleukin 11 receptor alpha subunit
Interleukin 11 receptor alpha subunit
Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene.-Further reading:...
and an incompletely characterized beta subunit.