Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.... of the immune system
Immune system
An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells.... . They may either be exogenous, as immunosuppressive drug
Immunosuppressive drug
Immunosuppressive drugs or immunosuppressive agents are medication that inhibit or prevent activity of the immune system. They are used in immunosuppression to:... s, or endogenous, as e. g. testosterone
Testosterone
Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testis of males and the ovaries of females, although small amounts are also secreted by the adrenal glands.... .
After an organ transplantation, the body will nearly always reject the new organ(s) due to differences in human leukocyte antigen
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans.The superlocus contains a large number of genes related to immune system function in humans.... haplotype
Haplotype
The term haplotype is a contraction of the term "Ploidy genotype." In genetics, a haplotype is a combination of alleles at multiple locus that are transmitted together on the same chromosome.... s between the donor and recipient. As a result, the immune system detects the new tissue as "hostile", and attempts to remove it by attacking it with recipient leukocytes, resulting in the death of the tissue.
Immunosuppressants are applied as a countermeasure; the side effect is that the body becomes extremely vulnerable to infections and malignancy, much like in an advanced HIV
HIV
Human immunodeficiency virus is a lentivirus that can lead to AIDS , a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections.... infection.
