IQSEC2
Encyclopedia
IQ motif and Sec7 domain 2 is a protein
that in humans is encoded by the IQSEC2 gene
.
for the ARF family of GTP-binding protein
s (see for example ARF1
).
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the IQSEC2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
The IQSEC2 gene encodes a guanine nucleotide exchange factorGuanine nucleotide exchange factor
Guanine nucleotide exchange factors activate monomeric GTPases by stimulating the release of guanosine diphosphate to allow binding of guanosine triphosphate . A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity...
for the ARF family of GTP-binding protein
G protein
G proteins are a family of proteins involved in transmitting chemical signals outside the cell, and causing changes inside the cell. They communicate signals from many hormones, neurotransmitters, and other signaling factors. G protein-coupled receptors are transmembrane receptors...
s (see for example ARF1
ARF1
ADP-ribosylation factor 1 is a protein that in humans is encoded by the ARF1 gene.-Interactions:ARF1 has been shown to interact with GGA3, PLD2, COPB1 and Muscarinic acetylcholine receptor M3.-Further reading:...
).