Hyper-IgM syndrome type 3
Encyclopedia
Hyper-IgM syndrome type 3 is a form of Hyper IgM syndrome
characterized by mutations of the CD40 gene. In this type, B cells cannot receive the signal from T cells to switch classes.
Hyper IgM syndrome
Hyper IgM syndrome is a family of genetic disorders in which the level of Immunoglobulin M antibodies is relatively high. The most common type is a result of a defect in a Th2 cell protein . The disorder causes immunodeficiencies, including a higher than normal susceptibility to various types of...
characterized by mutations of the CD40 gene. In this type, B cells cannot receive the signal from T cells to switch classes.