HSPA1A
Encyclopedia
Heat shock 70 kDa protein 1 is a protein
that in humans is encoded by the HSPA1A gene
.
with ASK1
, STUB1
, MSR1
, BAG3
, Parkin (ligase)
, Fanconi anemia, complementation group C
, GPR37
, HSF1
and AIFM1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the HSPA1A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
HSPA1A has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with ASK1
ASK1
Apoptosis signal-regulating kinase 1 also known as mitogen-activated protein kinase kinase kinase 5 is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway...
, STUB1
STUB1
STUB1 , also known as CHIP , is a human gene.- Function :...
, MSR1
MSR1
Macrophage scavenger receptor 1, also known as MSR1, is a protein which in humans is encoded by the MSR1 gene.MSR1 has also recently been designated CD204 .- Function :...
, BAG3
BAG3
BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene.BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination...
, Parkin (ligase)
Parkin (ligase)
Parkin is a protein which in humans is encoded by the PARK2 gene. The precise function of this protein is unknown; however, the protein is a component of a multiprotein E3 ubiquitin ligase complex which in turn is part of the ubiquitin-proteasome system that mediates the targeting of proteins for...
, Fanconi anemia, complementation group C
Fanconi anemia, complementation group C
-Interactions:Fanconi anemia, complementation group C has been shown to interact with STAT1, ZBTB32, GSTP1, Cdk1, SPTAN1, HSPA1A, FANCF, FANCA and FANCE.- External Links :* *...
, GPR37
GPR37
Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene.-Interactions:GPR37 has been shown to interact with HSPA1A and Parkin .-Further reading:...
, HSF1
HSF1
Heat shock factor protein 1 is a protein that in humans is encoded by the HSF1 gene.-Function:The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress...
and AIFM1
AIFM1
Apoptosis-inducing factor 1, mitochondrial is a protein that in humans is encoded by the AIFM1 gene.-Further reading:-External links:* on the Atlas of Genetics and Oncology...
.