HLA-B70
Encyclopedia
HLA-B (alpha)-β2MG with bound peptide | ||
Alleles | *1503, *1509, *1510, *1518, *1529, *1537 | |
Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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Shared data | ||
Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
HLA-B70 (B70) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies certain B*15 gene-allele protein products of HLA-B.
B70 is one of many split antigens of the broad antigen, B15
HLA-B15
HLA-B15 is an HLA-B serotype. The serotype identifies the B*15 gene-allele protein products of HLA-B.B15 is a broad antigen can be subdivided into several split antigens that are often used in characterization. These are B62, B63, B70, B71, B72, B75, B76, B77...
.
Serotype
B*15 | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | Sample |
allele | % | % | % | % | % | % | % | % | % | size (N) |
1 | 61 | 10 | 2569 | |||||||
53 | 65 | |||||||||
1 | 49 | 2 | 2 | 1 | 1204 | |||||
51 | 3 | 552 | ||||||||
19 | 21 | |||||||||
30 | 34 | |||||||||
Alleles link-out to IMGT/HLA Human leukocyte antigen The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and... Databease at EBI European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
Alleles
freq | ||
ref. | Population | (%) |
Burkina Faso Rimaibe | 13.8 | |
Guinea Bissau | 10.8 | |
Cameroon Pygmy Baka | 10.0 | |
South Africian Natal Zulu | 9.5 | |
Kenya Luo | 8.9 | |
Ivory Coast Akan Adiopodoume | 8.0 | |
Kenya Nandi | 7.9 | |
Cameroon Sawa | 7.7 | |
Zimbabwe Harare Shona | 7.7 | |
USA African America | 7.3 | |
Burkina Faso Fulani | 7.1 | |
Mali Bandiagara | 6.9 | |
Senegal Niokholo Mandenka | 6.9 | |
Cape Verde SE Islands | 6.5 | |
Kenya | 6.3 | |
Uganda Kampala | 6.2 | |
Sudanese | 6.0 | |
Zambia Lusaka | 5.7 | |
Cameroon Yaounde | 4.9 | |
Cape Verde NW Islands | 4.8 | |
Oman | 4.7 | |
Cameroon Bamileke | 4.5 | |
Tunisia Tunis | 4.5 | |
Cameroon Beti | 3.7 | |
Brazil Belo Horizonte | 3.2 | |
Azores Terceira Island | 2.4 | |
Madeira | 2.2 | |
Saudi Arabia Guraiat and Hail | 2.0 | |
Tunisia | 2.0 | |
United Arab Emerates | 1.5 | |
Brazil | 1.4 | |
Cuban White | 1.4 | |
Morocco Nador Metalsa | 1.4 | |
Mexico Mestizos | 1.2 | |
Italy Bergamo | 1.1 | |
Portugal North | 1.1 | |
American Samoa | 1.0 | |
Iran Baloch | 1.0 | |
Mexico Guadalajara Mestizos (2) | 1.0 | |
Azores Central Islands | 0.9 | |
Israel Ashk. and Non-Ashk. Jews | 0.9 | |
Taiwan Hakka | 0.9 | |
Croatia | 0.7 |
freq | ||
ref. | Population | (%) |
Burkina Faso Fulani | 4.1 | |
India West Coast Parsis | 3.0 | |
Spain Eastern Andalusia Gipsy | 3.0 | |
Mexico Mestizos | 2.4 | |
Italy South Campania | 1.2 | |
Burkina Faso Rimaibe | 1.1 | |
China Inner Mongolia | 1.0 | |
Mali Bandiagara | 0.7 | |
Czech Republic | 0.5 |
freq | ||
ref. | Population | (%) |
South Africian Natal Zulu | 8.5 | |
Zimbabwe Harare Shona | 8.4 | |
Ivory Coast Akan Adiopodoume | 5.7 | |
Kenya | 5.2 | |
Zambia Lusaka | 4.6 | |
Cameroon Sawa | 3.8 | |
Guinea Bissau | 3.8 | |
Kenya Luo | 3.6 | |
Senegal Niokholo Mandenka | 3.2 | |
Cameroon Beti | 2.8 | |
USA African Americans (3) | 2.7 | |
Uganda Kampala | 2.5 | |
Mexico Mestizos | 2.4 | |
Mali Bandiagara | 2.2 | |
Kenya Nandi | 1.7 | |
Brazil Belo Horizonte | 1.6 | |
Cameroon Bamileke | 1.3 | |
Cuban Mulatto | 1.2 | |
Cameroon Yaounde | 1.1 | |
Iran Baloch | 1.0 | |
Sudanese | 1.0 | |
Tunisia | 1.0 | |
Brazil Terena | 0.9 | |
Cape Verde NW Islands | 0.8 | |
United Arab Emerates | 0.8 | |
USA North American Natives | 0.8 | |
Guadalajara Mestizos (2) | 0.5 |
freq | ||
ref. | Population | (%) |
South Africa Natal Tamil | 4.1 | |
Autonomous Tibetans | 3.8 | |
India Mumbai Marathas | 3.7 | |
China North Han | 2.9 | |
USA Hawaii Okinawa | 2.9 | |
China Guangzhou Han | 2.4 | |
India Andhra Pradesh Golla | 2.4 | |
China Beijing | 2.3 | |
Taiwan Hakka | 1.8 | |
Japan | 1.7 | |
India North Delhi | 1.6 | |
China Inner Mongolia | 1.5 | |
China Qinghai Hui | 1.4 | |
Czech Republic | 1.4 | |
China Yunnan Nu | 1.3 | |
Shijiazhuang Tianjian Han | 1.1 | |
Ivory Coast Akan Adiopodoume | 1.1 | |
Senegal Niokholo Mandenka | 1.1 | |
Zambia Lusaka | 1.1 | |
Portugal Centre | 1.0 | |
Singapore Javanese Indonesians | 1.0 | |
Thailand (3) | 1.0 | |
South Korea (3) | 0.9 | |
Cape Verde Islands | 0.8 | |
France South East | 0.8 | |
Guinea Bissau | 0.8 | |
China South Han | 0.7 | |
China Yunnan Lisu | 0.7 | |
Russia Tuva (2) | 0.6 | |
Singapore Chinese Han | 0.6 | |
Spain Eastern Andalusia | 0.6 |