HLA-B40
Encyclopedia
HLA-B40 is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

 - B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. B40 is composed of the B60
HLA-B60
HLA-B60 is an HLA - B serotype. B60 is a split antigen serotype that recognizes certain B40 serotypes.-Serotype:...

 and B61
HLA-B61
HLA-B61 is an HLA - B serotype. B61 is a split antigen serotype that recognizes certain B40 serotypes.-Serotype:...

split antigen serotypes

Serotype

B60, B40, B61 serotype recognition of some HLA B*40 allele-group gene products
B*40 B60 B40 B61 Sample
allele % % % size (N)
4001 93 4 2 3854
B*40 B61 B40 B60 Sample
allele % % % size (N)
4002 80 6 8 1460
4003 62 23 31
4004 47 12 57
4006 75 5 5 585


B*4005 is poorly recognized by B40, B60, or B61.
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