Giles County High School's nickname in athletics is the Bobcats, the school mascot is a bobcat. The school is noted in athletics to be a basketball school, as it has won 2 girls state championships with numerous state tournament appearances; also, the boys team has had its share of success, winning their first state championship in 2003 under the guidance of head coach Billy Holt.

Academically speaking,State scores are slightly below average . English 1-4 is offered with Honors and AP options. Foreign Languages include Spanish and French. A journalism and video journalism class complete the Language Department. Giles County High's math options include Pre-Algebra, Algebra 1 and 2, Geometry, Pre-Calculus, Calculus and College Algebra. The Science Department features Biology 1 and 2, Chemistry 1 and 2, Physics, Ecology, Anatomy, Physical and Life Sciences. The Social Studies department offers World History, World Geography, American Government, United States History, Economics, International Business, Marketing, and Physiology. The Arts include Art 1-4, Theater, Chorus, and The GCHS Band of Gold.