GENCODE
Encyclopedia
GENCODE is a scientific project in genome research
Genome Research
Genome Research is a peer-reviewed scientific journal published by Cold Spring Harbor Laboratory Press. The focus of the journal is on genome-wide studies in any organism, including single gene studies that are placed in a genomic context. This scope includes both experimental and computational...

 and part of the ENCODE
ENCODE
ENCODE is a public research consortium launched by the US National Human Genome Research Institute in September 2003. The goal is to find all functional elements in the human genome, one of the most critical projects by NHGRI after it completed the successful Human Genome Project...

 (ENCyclopedia Of DNA Elements) scale-up project.

The aim of the GENCODE project is to annotate all evidence-based gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

 features in the entire human genome
Human genome
The human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs plus the small mitochondrial DNA. 22 of the 23 chromosomes are autosomal chromosome pairs, while the remaining pair is sex-determining...

 at a high accuracy. The result will be a set of annotations including all protein-coding loci
Locus (genetics)
In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...

 with alternatively transcribed variants, non-coding loci with transcript evidence, and pseudogenes.

The GENCODE project is an international effort headed by Tim Hubbard at the Wellcome Trust Sanger Institute.

External links

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK